Reaction profile

The FDA adverse-event record for intestinal congestion

43 FDA reports name intestinal congestion, a lower-volume reaction in the CVM extract (VeDDRA 326). Plate stamps and neighbourhood peers follow.

#1813 of 2,481
by report volume (all reactions)
43
reports citing this reaction
72.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Intestinal congestion has 43 reports now versus 43 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Intestinal congestion changes

FDA AER · VeDDRA plate

Code 326 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 43 reports
  • DEATH-HOT 72.1%
  • MID-PACK #1813/2481
  • PHOTO-FINISH Application site numb…
  • SPECIES-DOG Dog · 29
  • DRUG-LEAD Milbemycin Oxime… · 10
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site numbness (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Intestinal congestion

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Application site numb… · near43Elevated AST · near43INEFFECTIVE, PINWORMS · near43INEFFECTIVE, STOMACH… · near43Intestinal congestion · this…43Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Intestinal congestion

Intestinal congestion: high death-coded share in the FDA AER plate

Signature read: Intestinal congestion's 72.1% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 43 named reports in the openFDA extract. Death-coded share is upper-third: 31 of 43 reports (72.1% of named reports). Nearest volume peer: Application site numbness (±0 reports). Lead species Dog (29). Lead co-reported drug Milbemycin Oxime + Spinosad (10).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 29
Cattle 5
Cat 3
Pig 3
Chicken 1
Turkey 1
Horse 1

Breeds Most Affected

Retriever - Labrador 3
Crossbred Canine/dog 3
Boxer (German Boxer) 3
Terrier - Yorkshire 2
Domestic Shorthair 2
Holstein-Friesian also known as Holstein 2
Pit Bull 2
Dachshund - Miniature 2
Persian 1
Rottweiler 1

Associated Drugs

Milbemycin Oxime + Spinosad 10
Fluralaner Chew Tablets 5
Spinosad 4
Monensin Sodium 4
Ivermectin + Pyrantel As Pamoate Salt 4
Firocoxib 227 Mg Chewable 3
Rabies Vaccine 3
Pyrantel Pamoate 2
Dhlpp Vaccine 2
Grapiprant 2
Porcine Reproductive And Respiratory Syndrome (Respiratory Form) Modified Live Virus Vaccine 2
Live Attenuated Porcine Reproductive + Respiratory Syndrome Virus (Prrsv) Strain 2
Vitamin E 2
Emodepside + Praziquantel 1
Praziquantel + Pyrantel 1
Hygromycin B 1
Hyposensitization Injections 1
S-Adenosylmethionine 1
Diphenhydramine 1
Ivermectin 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Intestinal congestion (#1813 of 2,481 by report volume); death-coded 72.1%. PlainBreed reaction plate · death-coded share stamp 72.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →