Reaction profile

The FDA adverse-event record for excessive appetite

208 FDA adverse-event reports reference excessive appetite (VeDDRA 136). See the species, breeds, and drugs most associated with it below.

208
reports citing this reaction
9.1%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
Verify with FDA CVM →
208
Total Reports
19
Deaths
9.1%
Death Rate

Species Most Affected

Dog 134
Cat 72
Horse 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 42
Retriever - Labrador 12
Chihuahua 9
Shih Tzu 9
Boxer (German Boxer) 7
Dog (unknown) 7
Cat (unknown) 7
Domestic Longhair 6
Siamese 5
Crossbred Canine/dog 5

Associated Drugs

Trilostane 18
Oclacitinib Maleate 18
Carprofen 16
Bexagliflozin 14
Milbemycin Oxime + Spinosad 13
Mirtazapine 13
Bedinvetmab 13
Buprenorphine 12
Imidacloprid + Moxidectin 10
Cefovecin 9
Ivermectin + Pyrantel As Pamoate Salt 8
Prednisone 8
Spinosad 7
Afoxolaner 7
Maropitant Citrate 6
Tramadol 5
Milbemycin Oxime + Praziquantel 5
Fluralaner Chew Tablets 5
Insulin 5
Frunevetmab 5

Excessive appetite Reaction Insights

208 reports name Excessive appetite; 19 recorded a death outcome (9.1% of reported events, not a population-level mortality rate). VeDDRA code: 136.

By species: Dog (134 reports), Cat (72 reports), Horse (1 reports). By breed: Domestic Shorthair (42), Retriever - Labrador (12), Chihuahua (9).

Most co-reported drugs: Trilostane (18 reports), Oclacitinib Maleate (18 reports), Carprofen (16 reports), Bexagliflozin (14 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.