Spleen and reticulo-endothelial system disorder NOS
VeDDRA Code: 182
390 adverse event reports referencing this reaction
390
Total Reports
196
Deaths
5030.0%
Death Rate
Species Most Affected
Dog 356
Cat 26
Cattle 4
Chicken 1
Horse 1
Goat 1
Mouse 1
Breeds Most Affected
Retriever - Labrador 60
Domestic Shorthair 21
Retriever - Golden 21
Beagle 20
Crossbred Canine/dog 20
Shepherd Dog - German 15
Boxer (German Boxer) 15
Shepherd Dog - Australian 13
Shih Tzu 11
Chihuahua 9
Associated Drugs
Trilostane 60
Carprofen 53
Milbemycin Oxime + Spinosad 49
Spinosad 32
Afoxolaner 25
Maropitant Citrate 21
Grapiprant 20
Deracoxib 19
Fluralaner Chew Tablets 19
Polysulfated Glycosaminoglycan 18
Prednisone 17
Gabapentin 16
Tramadol 15
Oclacitinib Maleate 15
Ivermectin + Pyrantel As Pamoate Salt 12
Enrofloxacin 10
Moxidectin 10
Firocoxib 10
Cyclosporine 10
Milbemycin Oxime + Praziquantel 10
Source: FDA Center for Veterinary Medicine — Adverse Event Reports. Data reflects voluntary submissions and may not represent actual incidence rates.