Paraparesis

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VeDDRA Code: 699

155 adverse event reports referencing this reaction

155
Total Reports
46
Deaths
2970.0%
Death Rate

Species Most Affected

Dog 131
Cat 23
Hedgehog 1

Breeds Most Affected

Retriever - Labrador 21
Domestic Shorthair 13
Shepherd Dog - German 10
Retriever - Golden 6
Crossbred Canine/dog 6
Terrier - Bull - American Pit 6
Bulldog - French 6
Dachshund (unspecified) 5
Maltese 4
Domestic Longhair 4

Associated Drugs

Bedinvetmab 61
Carprofen 19
Gabapentin 19
Prednisone 12
Frunevetmab 10
Maropitant Citrate 8
Melarsomine Dihydrochloride 8
Oclacitinib Maleate 8
Milbemycin Oxime + Spinosad 7
Galliprant 7
Grapiprant 6
Rabies Vaccine 6
Buprenorphine 6
Polysulfated Glycosaminoglycan 6
Carporfen 6
Meloxicam 5
Afoxolaner 5
Clindamycin 5
Tramadol 5
Doxycycline 5

Data Summary

Metric Value
Total reports referencing reaction 155
Reports with fatal outcome 46
Case-fatality rate (reported events) 2970.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 699.

Paraparesis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 155 adverse event reports that reference Paraparesis as a reaction term, including 46 reports with a death outcome — a 2970.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 699, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Paraparesis appears most frequently in reports for Dog (131 reports), Cat (23 reports), Hedgehog (1 reports) — with Dog dominating at 131 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (21), Domestic Shorthair (13), Shepherd Dog - German (10). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Paraparesis are Bedinvetmab (61 reports), Carprofen (19 reports), Gabapentin (19 reports), Prednisone (12 reports), with Bedinvetmab appearing alongside this reaction in 61 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial