Reaction profile

The FDA adverse-event record for paraparesis

174 FDA adverse-event reports reference paraparesis (VeDDRA 699). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1112 of 2,481
by report volume (all reactions)
174
reports citing this reaction
29.3%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Paraparesis has 174 reports now versus 169 in that prior snapshot: 5 more (3.0%).

Report change
+5
Death-coded reports
+2
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Paraparesis changes

FDA AER · VeDDRA plate

Code 699 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 174 reports
  • DEATH-HOT 29.3%
  • MID-PACK #1112/2481
  • PHOTO-FINISH Cough, productive
  • SPECIES-DOG Dog · 146
  • DRUG-LEAD Bedinvetmab · 71
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Cough, productive (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Paraparesis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Elevated lactate · near175Cough, productive · near174Decreased blood urea… · near174Paraparesis · this reaction174Angioedema · near173Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Paraparesis

Paraparesis: high death-coded share in the FDA AER plate

Signature read: Paraparesis's 29.3% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 51 of 174 reports (29.3% of named reports). Nearest volume peer: Cough, productive (±0 reports). Lead species Dog (146). Lead co-reported drug Bedinvetmab (71).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 146
Cat 26
Hedgehog 1
Lion 1

Breeds Most Affected

Retriever - Labrador 23
Domestic Shorthair 16
Shepherd Dog - German 11
Retriever - Golden 10
Crossbred Canine/dog 9
Terrier - Bull - American Pit 6
Bulldog - French 6
Dachshund (unspecified) 5
Maltese 4
Deutsche Dogge, Great Dane 4

Associated Drugs

Bedinvetmab 71
Gabapentin 25
Carprofen 24
Prednisone 14
Maropitant Citrate 13
Frunevetmab 12
Oclacitinib Maleate 9
Melarsomine Dihydrochloride 8
Galliprant 8
Milbemycin Oxime + Spinosad 7
Meloxicam 7
Polysulfated Glycosaminoglycan 7
Anti-Il31 Mab Mcs Lot #1283563 6
Grapiprant 6
Rabies Vaccine 6
Buprenorphine 6
Carporfen 6
Moxidectin 5
Afoxolaner 5
Clindamycin 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Paraparesis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (29.3% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Paraparesis (#1112 of 2,481 by report volume); death-coded 29.3%. PlainBreed reaction plate · death-coded share stamp 29.3% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →