Reaction profile

The FDA adverse-event record for motor neurone disease

14 FDA adverse-event reports reference motor neurone disease (VeDDRA 1621). See the species, breeds, and drugs most associated with it below.

14
reports citing this reaction
14.3%
death-coded share
Dog
most-affected species
Prednisone
most-associated drug
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14
Total Reports
2
Deaths
14.3%
Death Rate

Species Most Affected

Dog 12
Cat 2

Breeds Most Affected

Schnauzer - Miniature 2
Mixed (Dog) 2
Domestic Shorthair 2
Pit Bull 2
Shepherd Dog - German 1
Retriever - Labrador 1
Terrier - West Highland White 1
Retriever - Golden 1
Crossbred Canine/dog 1
Mastiff (unspecified) 1

Associated Drugs

Prednisone 3
Milbemycin Oxime + Spinosad 2
Doxycycline 2
Tramadol 2
Gabapentin 2
Fluralaner 13.64% 12-Week Chew 2
Melarsomine 1
Vaccines (Unknown) 1
Fenbendazol Suspension 1
Canine Bb/Pi3/Adeno 2 Lv/Lb 1
Canine Da2Ppv (Orig S-P Us) Lv 1
Rabies In Hhh Adj Pfizer Kv 1
Milbemycin Oxime, Lufenuron 1
Sarolaner 1
Moxidectin 1
Diphenhydramine Hcl 1
Dexamethasone 1
Lisinopril 1
Antioxidants 1
Tiletamine Hcl & Zolazepam Hcl) 1

Motor neurone disease Reaction Insights

14 reports name Motor neurone disease; 2 recorded a death outcome (14.3% of reported events, not a population-level mortality rate). VeDDRA code: 1621.

By species: Dog (12 reports), Cat (2 reports). By breed: Schnauzer - Miniature (2), Mixed (Dog) (2), Domestic Shorthair (2).

Most co-reported drugs: Prednisone (3 reports), Milbemycin Oxime + Spinosad (2 reports), Doxycycline (2 reports), Tramadol (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.