Reaction profile

The FDA adverse-event record for eye sore and red

16 FDA reports name eye sore and red, a lower-volume reaction in the CVM extract (VeDDRA 1459). Plate stamps and neighbourhood peers follow.

#2270 of 2,481
by report volume (all reactions)
16
reports citing this reaction
12.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Eye sore and red has 16 reports now versus 16 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Eye sore and red changes

FDA AER · VeDDRA plate

Code 1459 VOL-TRACE

VOL-TRACE · DEATH-ELEV · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 16 reports
  • DEATH-ELEV 12.5%
  • BOTTOM-DECILE #2270/2481
  • PHOTO-FINISH Abdominal transudate
  • SPECIES-DOG Dog · 9
  • DRUG-LEAD Milbemycin Oxime… · 2
  • DESK-WIDE 11 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abdominal transudate (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Eye sore and red

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abdominal transudate · near16Abnormal rectal palpa… · near16AMMONIA INCREASED, BL… · near16Application site gran… · near16Eye sore and red · this reac…16Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Eye sore and red

What the FDA AER plate says about Eye sore and red

Signature read: 16 reports place Eye sore and red in the lower third of FDA AER volume (#2270 of 2,481). Report volume is lower-third scale: 16 named reports in the openFDA extract. 2 of 16 reports were death-coded (12.5% of named reports, not a population mortality rate). Nearest volume peer: Abdominal transudate (±0 reports). Lead species Dog (9). Lead co-reported drug Milbemycin Oxime + Spinosad (2).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 9
Human 6
Cat 1

Breeds Most Affected

Unknown 6
Terrier - Jack Russell 1
Terrier - Yorkshire 1
Pug 1
Pekingese 1
Spaniel - Cocker American 1
Crossbred Canine/dog 1
Siberian Husky 1
Dog (unknown) 1
Domestic Shorthair 1

Associated Drugs

Milbemycin Oxime + Spinosad 2
Thiabendazole/Neomycin/Dexamethason 1
Deracoxib 1
Clindamycin 1
Buprenorphine 1
Anesthesia 1
Ivermectin/Pyrantel 1
Dinotefuran/Pyriproxyfen/Permethrin 1
Atipamezole Hydrochloride 1
Recombinant Human Insulin 1
Diphenhydramine 1
Etofenprox, Piperonyl Butoxide, N-Octyl Bicycloheptene Dicarboximide 1
Dimethyl Sulfoxide; Fluocinolone Acetonide 1
Selamectin 1
Fluralaner Chew Tablets 1
Meloxicam 1
Oxytetracycline Dihydrate 1
Afoxolaner 1
Ketoconazole 1
Imidacloprid, Moxidectin 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Eye sore and red (#2270 of 2,481 by report volume); death-coded 12.5%. PlainBreed reaction plate · report volume stamp 16 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →