Reaction profile

The FDA adverse-event record for eye sore and red

16 FDA adverse-event reports reference eye sore and red (VeDDRA 1459). See the species, breeds, and drugs most associated with it below.

16
reports citing this reaction
12.5%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
16
Total Reports
2
Deaths
12.5%
Death Rate

Species Most Affected

Dog 9
Human 6
Cat 1

Breeds Most Affected

Unknown 6
Terrier - Jack Russell 1
Terrier - Yorkshire 1
Pug 1
Pekingese 1
Spaniel - Cocker American 1
Crossbred Canine/dog 1
Siberian Husky 1
Dog (unknown) 1
Domestic Shorthair 1

Associated Drugs

Milbemycin Oxime + Spinosad 2
Thiabendazole/Neomycin/Dexamethason 1
Deracoxib 1
Clindamycin 1
Buprenorphine 1
Anesthesia 1
Ivermectin/Pyrantel 1
Dinotefuran/Pyriproxyfen/Permethrin 1
Atipamezole Hydrochloride 1
Recombinant Human Insulin 1
Diphenhydramine 1
Etofenprox, Piperonyl Butoxide, N-Octyl Bicycloheptene Dicarboximide 1
Dimethyl Sulfoxide; Fluocinolone Acetonide 1
Selamectin 1
Fluralaner Chew Tablets 1
Meloxicam 1
Oxytetracycline Dihydrate 1
Afoxolaner 1
Ketoconazole 1
Imidacloprid, Moxidectin 1

Eye sore and red Reaction Insights

16 reports name Eye sore and red; 2 recorded a death outcome (12.5% of reported events, not a population-level mortality rate). VeDDRA code: 1459.

By species: Dog (9 reports), Human (6 reports), Cat (1 reports). By breed: Unknown (6), Terrier - Jack Russell (1), Terrier - Yorkshire (1).

Most co-reported drugs: Milbemycin Oxime + Spinosad (2 reports), Thiabendazole/Neomycin/Dexamethason (1 reports), Deracoxib (1 reports), Clindamycin (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.