Head tremor

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VeDDRA Code: 1900

2,391 adverse event reports referencing this reaction

2,391
Total Reports
134
Deaths
560.0%
Death Rate

Species Most Affected

Dog 2,063
Cat 307
Horse 8
Cattle 5
Pig 3
Guinea Pig 1
Rabbit 1
Unknown 1
Other 1
Donkey 1

Breeds Most Affected

Retriever - Labrador 237
Domestic Shorthair 198
Crossbred Canine/dog 140
Bulldog 126
Retriever - Golden 109
Boxer (German Boxer) 101
Terrier - Yorkshire 74
Chihuahua 73
Shepherd Dog - Australian 65
Dog (unknown) 51

Associated Drugs

Pyrantel Pamoate;Sarolaner 318
Afoxolaner 316
Sarolaner 270
Milbemycin Oxime + Spinosad 224
Ivermectin + Pyrantel As Pamoate Salt 128
Fluralaner 13.64% 12-Week Chew 112
Fluralaner Chew Tablets 99
Milbemycin Oxime + Praziquantel 76
Bedinvetmab 75
Oclacitinib Maleate 70
Lotilaner 68
Gabapentin 65
Moxidectin 59
Maropitant Citrate 53
Imidacloprid + Moxidectin 52
Selamectin 52
Carprofen 49
Fluralaner Spot-On Solution 48
Spinosad 46
Prednisone 46

Data Summary

Metric Value
Total reports referencing reaction 2,391
Reports with fatal outcome 134
Case-fatality rate (reported events) 560.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1900.

Head tremor Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 2,391 adverse event reports that reference Head tremor as a reaction term, including 134 reports with a death outcome — a 560.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1900, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Head tremor appears most frequently in reports for Dog (2,063 reports), Cat (307 reports), Horse (8 reports) — with Dog dominating at 2,063 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (237), Domestic Shorthair (198), Crossbred Canine/dog (140). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Head tremor are Pyrantel Pamoate;Sarolaner (318 reports), Afoxolaner (316 reports), Sarolaner (270 reports), Milbemycin Oxime + Spinosad (224 reports), with Pyrantel Pamoate;Sarolaner appearing alongside this reaction in 318 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial