Reaction profile

The FDA adverse-event record for head tremor

2,391 FDA adverse-event reports reference head tremor (VeDDRA 1900). See the species, breeds, and drugs most associated with it below.

2,391
reports citing this reaction
5.6%
death-coded share
Dog
most-affected species
Pyrantel Pamoate;Sarolaner
most-associated drug
Verify with FDA CVM →
2,391
Total Reports
134
Deaths
5.6%
Death Rate

Species Most Affected

Dog 2,063
Cat 307
Horse 8
Cattle 5
Pig 3
Guinea Pig 1
Rabbit 1
Unknown 1
Other 1
Donkey 1

Breeds Most Affected

Retriever - Labrador 237
Domestic Shorthair 198
Crossbred Canine/dog 140
Bulldog 126
Retriever - Golden 109
Boxer (German Boxer) 101
Terrier - Yorkshire 74
Chihuahua 73
Shepherd Dog - Australian 65
Dog (unknown) 51

Associated Drugs

Pyrantel Pamoate;Sarolaner 318
Afoxolaner 316
Sarolaner 270
Milbemycin Oxime + Spinosad 224
Ivermectin + Pyrantel As Pamoate Salt 128
Fluralaner 13.64% 12-Week Chew 112
Fluralaner Chew Tablets 99
Milbemycin Oxime + Praziquantel 76
Bedinvetmab 75
Oclacitinib Maleate 70
Lotilaner 68
Gabapentin 65
Moxidectin 59
Maropitant Citrate 53
Imidacloprid + Moxidectin 52
Selamectin 52
Carprofen 49
Fluralaner Spot-On Solution 48
Spinosad 46
Prednisone 46

Head tremor Reaction Insights

2,391 reports name Head tremor; 134 recorded a death outcome (5.6% of reported events, not a population-level mortality rate). VeDDRA code: 1900.

By species: Dog (2,063 reports), Cat (307 reports), Horse (8 reports). By breed: Retriever - Labrador (237), Domestic Shorthair (198), Crossbred Canine/dog (140).

Most co-reported drugs: Pyrantel Pamoate;Sarolaner (318 reports), Afoxolaner (316 reports), Sarolaner (270 reports), Milbemycin Oxime + Spinosad (224 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.