Leukaemia

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VeDDRA Code: 171

85 adverse event reports referencing this reaction

85
Total Reports
53
Deaths
6240.0%
Death Rate

Species Most Affected

Dog 68
Cat 17

Breeds Most Affected

Domestic Shorthair 13
Retriever - Golden 6
Shepherd Dog - German 6
Retriever - Labrador 5
Shih Tzu 4
Pit Bull 3
Dog (unknown) 3
Bulldog 3
Dachshund (unspecified) 2
Dog (other) 2

Associated Drugs

Oclacitinib Maleate 24
Milbemycin Oxime + Spinosad 8
Maropitant Citrate 7
Cefovecin 6
Ivermectin + Pyrantel As Pamoate Salt 6
Prednisone 5
Selamectin 5
Carprofen 5
Anti-Il31 Mab Mcs Lot #1283563 5
Cyclosporine A 4
Spinosad 4
Afoxolaner 4
Enrofloxacin 3
Moxidectin 3
Emodepside + Praziquantel 3
Fluralaner Chew Tablets 3
Milbemycin Oxime 3
Cyclosporine 3
Doxycycline 3
Imidacloprid + Permethrin + N-Methylpyrolidone 2

Data Summary

Metric Value
Total reports referencing reaction 85
Reports with fatal outcome 53
Case-fatality rate (reported events) 6240.0%
Species observed 2
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 171.

Leukaemia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 85 adverse event reports that reference Leukaemia as a reaction term, including 53 reports with a death outcome — a 6240.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 171, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Leukaemia appears most frequently in reports for Dog (68 reports), Cat (17 reports) — with Dog dominating at 68 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (13), Retriever - Golden (6), Shepherd Dog - German (6). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Leukaemia are Oclacitinib Maleate (24 reports), Milbemycin Oxime + Spinosad (8 reports), Maropitant Citrate (7 reports), Cefovecin (6 reports), with Oclacitinib Maleate appearing alongside this reaction in 24 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial