Reaction profile

The FDA adverse-event record for albumin/globulin ratio hi, bld

18 FDA reports name albumin/globulin ratio hi, bld, a lower-volume reaction in the CVM extract (VeDDRA 99162). Plate stamps and neighbourhood peers follow.

#2200 of 2,481
by report volume (all reactions)
18
reports citing this reaction
16.7%
death-coded share
Dog
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. ALBUMIN/GLOBULIN RATIO HI, BLD has 18 reports now versus 18 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to ALBUMIN/GLOBULIN RATIO HI, BLD changes

FDA AER · VeDDRA plate

Code 99162 VOL-TRACE

VOL-TRACE · DEATH-ELEV · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 18 reports
  • DEATH-ELEV 16.7%
  • LOWER-Q #2200/2481
  • PHOTO-FINISH Application site skin…
  • SPECIES-DOG Dog · 17
  • DRUG-LEAD Milbemycin Oxime… · 4
  • DESK-WIDE 15 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site skin slough (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around ALBUMIN/GLOBULIN RATIO HI, BLD

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ALBUMIN/GLOBULIN RATI… · thi…18Application site skin… · near18Bone marrow hypoplasia · near18Cognitive disturbance · near18Complication of diabe… · near18Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around ALBUMIN/GLOBULIN RATIO HI, BLD

What the FDA AER plate says about ALBUMIN/GLOBULIN RATIO HI, BLD

Signature read: 18 reports place ALBUMIN/GLOBULIN RATIO HI, BLD in the lower third of FDA AER volume (#2200 of 2,481). Report volume is lower-third scale: 18 named reports in the openFDA extract. 3 of 18 reports were death-coded (16.7% of named reports, not a population mortality rate). Nearest volume peer: Application site skin slough (±0 reports). Lead species Dog (17). Lead co-reported drug Milbemycin Oxime + Spinosad (4).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 17
Cat 1

Breeds Most Affected

Retriever - Labrador 3
Dachshund - Miniature 2
Shepherd Dog - Australian 1
Poodle (unspecified) 1
Retriever (unspecified) 1
Domestic (unspecified) 1
Poodle - Toy 1
Great Pyrenees 1
Schnauzer - Miniature 1
Havanese 1

Associated Drugs

Milbemycin Oxime + Spinosad 4
Ivermectin + Pyrantel As Pamoate Salt 4
Trilostane 2
Afoxolaner 2
Glycosaminoglycan Polysulfate 1
Vitamin B 1
Omega 3 1
Firocoxib 1
Robenacoxib 1
Spinosad 1
Fluralaner Chew Tablets 1
Afoxolaner 2.27% Chewable Tablet (28.3 Mg) 1
Fluralaner 13.64% 12-Week Chew 1
Ursodiol 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for ALBUMIN/GLOBULIN RATIO HI, BLD (#2200 of 2,481 by report volume); death-coded 16.7%. PlainBreed reaction plate · report volume stamp 18 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →