Reaction profile

The FDA adverse-event record for albumin/globulin ratio hi, bld

18 FDA adverse-event reports reference albumin/globulin ratio hi, bld (VeDDRA 99162). See the species, breeds, and drugs most associated with it below.

18
reports citing this reaction
16.7%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
18
Total Reports
3
Deaths
16.7%
Death Rate

Species Most Affected

Dog 17
Cat 1

Breeds Most Affected

Retriever - Labrador 3
Dachshund - Miniature 2
Shepherd Dog - Australian 1
Poodle (unspecified) 1
Retriever (unspecified) 1
Domestic (unspecified) 1
Poodle - Toy 1
Great Pyrenees 1
Schnauzer - Miniature 1
Havanese 1

Associated Drugs

Milbemycin Oxime + Spinosad 4
Ivermectin + Pyrantel As Pamoate Salt 4
Trilostane 2
Afoxolaner 2
Glycosaminoglycan Polysulfate 1
Vitamin B 1
Omega 3 1
Firocoxib 1
Robenacoxib 1
Spinosad 1
Fluralaner Chew Tablets 1
Afoxolaner 2.27% Chewable Tablet (28.3 Mg) 1
Fluralaner 13.64% 12-Week Chew 1
Ursodiol 1

ALBUMIN/GLOBULIN RATIO HI, BLD Reaction Insights

18 reports name ALBUMIN/GLOBULIN RATIO HI, BLD; 3 recorded a death outcome (16.7% of reported events, not a population-level mortality rate). VeDDRA code: 99162.

By species: Dog (17 reports), Cat (1 reports). By breed: Retriever - Labrador (3), Dachshund - Miniature (2), Shepherd Dog - Australian (1).

Most co-reported drugs: Milbemycin Oxime + Spinosad (4 reports), Ivermectin + Pyrantel As Pamoate Salt (4 reports), Trilostane (2 reports), Afoxolaner (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.