Paresis

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VeDDRA Code: 698

480 adverse event reports referencing this reaction

480
Total Reports
135
Deaths
2810.0%
Death Rate

Species Most Affected

Dog 398
Cat 54
Horse 8
Cattle 7
Turkey 6
Chicken 2
Pig 2
Rabbit 1
Human 1
Goose 1

Breeds Most Affected

Retriever - Labrador 57
Crossbred Canine/dog 31
Shepherd Dog - German 20
Retriever - Golden 20
Chihuahua 18
Domestic (unspecified) 17
Domestic Shorthair 15
Terrier - Yorkshire 14
Shih Tzu 13
Dog (unknown) 11

Associated Drugs

Bedinvetmab 126
Carprofen 75
Gabapentin 45
Milbemycin Oxime + Spinosad 23
Spinosad 21
Moxidectin 21
Prednisone 16
Oclacitinib Maleate 16
Afoxolaner 15
Meloxicam 14
Galliprant 14
Melarsomine Dihydrochloride 12
Maropitant Citrate 11
Polysulfated Glycosaminoglycan 11
Enrofloxacin 10
Firocoxib 9
Selamectin 8
Cefovecin Sodium 8
Maropitant 8
Tramadol 8

Data Summary

Metric Value
Total reports referencing reaction 480
Reports with fatal outcome 135
Case-fatality rate (reported events) 2810.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 698.

Paresis Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 480 adverse event reports that reference Paresis as a reaction term, including 135 reports with a death outcome — a 2810.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 698, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Paresis appears most frequently in reports for Dog (398 reports), Cat (54 reports), Horse (8 reports) — with Dog dominating at 398 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (57), Crossbred Canine/dog (31), Shepherd Dog - German (20). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Paresis are Bedinvetmab (126 reports), Carprofen (75 reports), Gabapentin (45 reports), Milbemycin Oxime + Spinosad (23 reports), with Bedinvetmab appearing alongside this reaction in 126 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial