Reaction profile

The FDA adverse-event record for hyperparathyroidism

21 FDA adverse-event reports reference hyperparathyroidism (VeDDRA 397). See the species, breeds, and drugs most associated with it below.

21
reports citing this reaction
19.0%
death-coded share
Dog
most-affected species
Trilostane
most-associated drug
Verify with FDA CVM →
21
Total Reports
4
Deaths
19.0%
Death Rate

Species Most Affected

Dog 21

Breeds Most Affected

Terrier - Jack Russell 2
Crossbred Canine/dog 2
Retriever - Golden 2
Shepherd Dog - Australian 2
Terrier - Yorkshire 1
Bichon Frise 1
Collie (unspecified) 1
Dog (unknown) 1
Boxer (German Boxer) 1
Collie - Smooth-haired 1

Associated Drugs

Trilostane 7
Milbemycin Oxime + Praziquantel 3
Oclacitinib Maleate 3
Bedinvetmab 3
Milbemycin Oxime + Spinosad 2
Cosequin 2
Fish Oil Supplement 2
Firocoxib 1
Fluralaner Chew Tablets 1
Capromorelin 1
Fluralaner 1
Avocado/Soybean Unsaponifiable + Glucosamine + Sodium Chondroitin Sulfate 1
Oclacitinib 1
Grapiprant 1
Anti-Il31 Mab Mcs Lot #1283563 1
Polysulfated Glycosaminoglycan 1
Carprofen 1
Apomorphine 1
Hydrogen Peroxide 1
Fluids 1

Hyperparathyroidism Reaction Insights

21 reports name Hyperparathyroidism; 4 recorded a death outcome (19.0% of reported events, not a population-level mortality rate). VeDDRA code: 397.

By species: Dog (21 reports). By breed: Terrier - Jack Russell (2), Crossbred Canine/dog (2), Retriever - Golden (2).

Most co-reported drugs: Trilostane (7 reports), Milbemycin Oxime + Praziquantel (3 reports), Oclacitinib Maleate (3 reports), Bedinvetmab (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.