Reaction profile

The FDA adverse-event record for ineffective, worms

465 FDA reports name ineffective, worms, a high-volume reaction in the CVM extract (VeDDRA 99160). Plate stamps and neighbourhood peers follow.

#671 of 2,481
by report volume (all reactions)
465
reports citing this reaction
4.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. INEFFECTIVE, WORMS has 465 reports now versus 465 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to INEFFECTIVE, WORMS changes

FDA AER · VeDDRA plate

Code 99160 VOL-LOW

VOL-LOW · DEATH-LOW · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 465 reports
  • DEATH-LOW 4.1%
  • MID-PACK #671/2481
  • PHOTO-FINISH Alkaline urine
  • SPECIES-DOG Dog · 363
  • DRUG-LEAD Ivermectin + Pyra… · 104
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Alkaline urine (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around INEFFECTIVE, WORMS

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Missing Labels · near466Alkaline urine · near465Ear pain · near465INEFFECTIVE, WORMS · this re…465Hepatitis · near463Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around INEFFECTIVE, WORMS

INEFFECTIVE, WORMS: low death-coded share in the FDA AER plate

Signature read: INEFFECTIVE, WORMS's 4.1% death-coded share is among the lowest in the openFDA reaction corpus. Report volume is upper-third scale: 465 named reports in the openFDA extract. Death-coded share is lower-third: 19 of 465 reports (4.1% of named reports). Nearest volume peer: Alkaline urine (±0 reports). Lead species Dog (363). Lead co-reported drug Ivermectin + Pyrantel As Pamoate Salt (104).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Ivermectin + Pyrantel As Pamoate Salt appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 363
Cattle 47
Cat 31
Sheep 8
Horse 6
Goat 4
Pig 2
Unknown 1
Buffalo 1
Quail 1

Breeds Most Affected

Dog (unknown) 66
Retriever - Labrador 43
Crossbred Canine/dog 30
Retriever - Golden 20
Shepherd Dog - German 17
Mixed (Cattle) 16
Domestic Shorthair 16
Cattle (other) 14
Pit Bull 11
Chihuahua 11

Associated Drugs

Ivermectin + Pyrantel As Pamoate Salt 104
Febantel + Praziquantel + Pyrantel Pamoate 55
Milbemycin Oxime + Spinosad 43
Fenbendazol Granules 29
Lufenuron + Milbemycin Oxime 28
Imidacloprid + Moxidectin 19
Praziquantel + Pyrantel Pamoate 18
Albendazole 16
Lufenuron + Milbemycin Oxime + Praziquantel 16
Selamectin 15
Praziquantel 14
Doramectin 13
Milbemycin Oxime, Lufenuron 11
Fenbendazol Suspension 11
Praziquantel/Pyrantel Pamoate/Febantel 9
Milbemycin Oxime 6
Ivermectin 6
Pyrantel Pamoate (Pyrantel Embonate) 6
Afoxolaner 6
Doramectin; Phenol 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for INEFFECTIVE, WORMS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (465 here).

Similar death-coded share

Nearest other reactions by death-coded share (4.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for INEFFECTIVE, WORMS (#671 of 2,481 by report volume); death-coded 4.1%. PlainBreed reaction plate · death-coded share stamp 4.1% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →