Reaction profile

The FDA adverse-event record for lack of efficacy (ectoparasite) - lice

1,110 FDA adverse-event reports reference lack of efficacy (ectoparasite) - lice (VeDDRA 2651). See the species, breeds, and drugs most associated with it below.

1,110
reports citing this reaction
0.5%
death-coded share
Cattle
most-affected species
Doramectin
most-associated drug
Verify with FDA CVM →
1,110
Total Reports
6
Deaths
0.5%
Death Rate

Species Most Affected

Cattle 1,076
Dog 19
Cat 12
Pig 1
Iguana 1
Goat 1

Breeds Most Affected

Aberdeen Angus 280
Cattle (unknown) 219
Cattle (other) 209
Crossbred Bovine/Cattle 131
Mixed (Cattle) 118
Holstein-Friesian also known as Holstein 47
Hereford cattle 17
Charolais 17
Simmental 14
Unknown 10

Associated Drugs

Doramectin 364
Moxidectin 208
Portech App Gun 65 Ml Ivomec/Eprinex 166
Ivermectin 152
Ivermectin 0.5% Pour-On Topical Solution 145
Eprinomectin 5 Mg/Ml Pour-On Solution 79
Eprinomectin 44
Eprinomectin 0.5% Pour-On 35
Ivermectin 0.5% Pour-On 19
Device - Applicator Gun 18
Selamectin 11
Ivermectin Pour-On Cattle 11
Eprinomectin Topical 10
65Ml Powered Ivomec/Eprinex Applicator 7
Breaze App Gun 80 Ml Ivomec/Eprinex 7
Clorsulon, Ivermectin 6
Ivermectin(1%)/Clorsulon(10%) Injection 5
Doramectin; Phenol 4
Merial La Polypropylene Syringe 4
Afoxolaner 4

Lack of efficacy (ectoparasite) - lice Reaction Insights

1,110 reports name Lack of efficacy (ectoparasite) - lice; 6 recorded a death outcome (0.5% of reported events, not a population-level mortality rate). VeDDRA code: 2651.

By species: Cattle (1,076 reports), Dog (19 reports), Cat (12 reports). By breed: Aberdeen Angus (280), Cattle (unknown) (219), Cattle (other) (209).

Most co-reported drugs: Doramectin (364 reports), Moxidectin (208 reports), Portech App Gun 65 Ml Ivomec/Eprinex (166 reports), Ivermectin (152 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.