Reaction profile

The FDA adverse-event record for hyperhidrosis

104 FDA adverse-event reports reference hyperhidrosis (VeDDRA 975). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1375 of 2,481
by report volume (all reactions)
104
reports citing this reaction
12.5%
death-coded share
Horse
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hyperhidrosis has 104 reports now versus 104 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hyperhidrosis changes

FDA AER · VeDDRA plate

Code 975 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-HORSE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 104 reports
  • DEATH-ELEV 12.5%
  • MID-PACK #1375/2481
  • PHOTO-FINISH Application site hot…
  • SPECIES-HORSE Horse · 91
  • DRUG-LEAD Ceftiofur Crystal… · 10
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Application site hot spot (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Hyperhidrosis

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Application site hot… · near104Congestion of mucous… · near104Furunculosis · near104Hyperhidrosis · this reaction104Lack of efficacy (myc… · near104Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hyperhidrosis

What the FDA AER plate says about Hyperhidrosis

Signature read: 13 death-coded reports is the most distinctive absolute-outcome stamp on Hyperhidrosis. Report volume sits in the middle third of the reaction corpus. 13 of 104 reports were death-coded (12.5% of named reports, not a population mortality rate). Nearest volume peer: Application site hot spot (±0 reports). Lead species Horse (91). Lead co-reported drug Ceftiofur Crystalline Free Acid (10).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Ceftiofur Crystalline Free Acid appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Horse 91
Human 7
Cattle 3
Dog 1
Cat 1
Other Equids 1

Breeds Most Affected

Quarter Horse 24
Horse (unknown) 12
Thoroughbred 10
Arab 9
Unknown 7
Paint 6
Horse (other) 6
Tennessee Walking Horse 4
Crossbred Equine/horse 4
Percheron 2

Associated Drugs

Ceftiofur Crystalline Free Acid 10
Ivermectin 9
Clenbuterol Hydrochloride 7
Detomidine 7
Pergolide Mesylate 7
Detomidine Hydrochloride 7
Ivermectin, Praziquantel 6
Flunixin Meglumine 6
Butorphanol Tartrate 4
Zilpaterol 4
Firocoxib 3
Ponazuril 3
Fenbendazole 3
Polysulfated Glycosaminoglycan 3
Ceftiofur Sodium 2
Glycosaminoglycan Polysulfate 2
Dinoprost Tromethamine 2
Ketamine Hydrochloride 2
Cloprostenol Sodium 2
Mepivacaine Hydrochloride 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Hyperhidrosis, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (12.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hyperhidrosis (#1375 of 2,481 by report volume); death-coded 12.5%. PlainBreed reaction plate · death-coded report count stamp 13 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →