Reaction profile

The FDA adverse-event record for hyperhidrosis

104 FDA adverse-event reports reference hyperhidrosis (VeDDRA 975). See the species, breeds, and drugs most associated with it below.

104
reports citing this reaction
12.5%
death-coded share
Horse
most-affected species
Ceftiofur Crystalline Free Acid
most-associated drug
Verify with FDA CVM →
104
Total Reports
13
Deaths
12.5%
Death Rate

Species Most Affected

Horse 91
Human 7
Cattle 3
Dog 1
Cat 1
Other Equids 1

Breeds Most Affected

Quarter Horse 24
Horse (unknown) 12
Thoroughbred 10
Arab 9
Unknown 7
Paint 6
Horse (other) 6
Tennessee Walking Horse 4
Crossbred Equine/horse 4
Percheron 2

Associated Drugs

Ceftiofur Crystalline Free Acid 10
Ivermectin 9
Clenbuterol Hydrochloride 7
Detomidine 7
Pergolide Mesylate 7
Detomidine Hydrochloride 7
Ivermectin, Praziquantel 6
Flunixin Meglumine 6
Butorphanol Tartrate 4
Zilpaterol 4
Ponazuril 3
Firocoxib 3
Fenbendazole 3
Polysulfated Glycosaminoglycan 3
Ceftiofur Sodium 2
Dinoprost Tromethamine 2
Glycosaminoglycan Polysulfate 2
Ketamine Hydrochloride 2
Cloprostenol Sodium 2
Mepivacaine Hydrochloride 2

Hyperhidrosis Reaction Insights

104 reports name Hyperhidrosis; 13 recorded a death outcome (12.5% of reported events, not a population-level mortality rate). VeDDRA code: 975.

By species: Horse (91 reports), Human (7 reports), Cattle (3 reports). By breed: Quarter Horse (24), Horse (unknown) (12), Thoroughbred (10).

Most co-reported drugs: Ceftiofur Crystalline Free Acid (10 reports), Ivermectin (9 reports), Clenbuterol Hydrochloride (7 reports), Detomidine (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.