Reaction profile

The FDA adverse-event record for spleen nodules

70 FDA adverse-event reports reference spleen nodules (VeDDRA 2900). See the species, breeds, and drugs most associated with it below.

70
reports citing this reaction
41.4%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
70
Total Reports
29
Deaths
41.4%
Death Rate

Species Most Affected

Dog 70

Breeds Most Affected

Retriever - Labrador 16
Crossbred Canine/dog 11
Retriever - Golden 8
Shepherd Dog - German 4
Bichon Frise 4
Sheepdog - Shetland 2
Terrier - Bull - Staffordshire 2
Rottweiler 2
Doberman Pinscher 2
Beagle 2

Associated Drugs

Bedinvetmab 39
Carprofen 21
Gabapentin 16
Maropitant Citrate 15
Oclacitinib Maleate 7
Prednisone 6
Leptospirosis Vaccine 6
Anti-Il31 Mab Mcs Lot #1283563 5
Afoxolaner 5
Doxycycline 5
Capromorelin 5
Pyrantel Pamoate;Sarolaner 5
Trazodone 4
Moxidectin 4
Insulin Injectable Vial 3
Galliprant 3
Ivermectin + Pyrantel As Pamoate Salt 3
Atipamezole 3
Omeprazole 3
Bordetella Vaccine 3

Spleen nodules Reaction Insights

70 reports name Spleen nodules; 29 recorded a death outcome (41.4% of reported events, not a population-level mortality rate). VeDDRA code: 2900.

By species: Dog (70 reports). By breed: Retriever - Labrador (16), Crossbred Canine/dog (11), Retriever - Golden (8).

Most co-reported drugs: Bedinvetmab (39 reports), Carprofen (21 reports), Gabapentin (16 reports), Maropitant Citrate (15 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.