Reaction profile

The FDA adverse-event record for injection site skin scaling

23 FDA adverse-event reports reference injection site skin scaling (VeDDRA 2203). See the species, breeds, and drugs most associated with it below.

23
reports citing this reaction
4.3%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
23
Total Reports
1
Deaths
4.3%
Death Rate

Species Most Affected

Dog 13
Cat 8
Horse 1
Cattle 1

Breeds Most Affected

Domestic Shorthair 5
Chihuahua 2
Doberman Pinscher 2
Crossbred Canine/dog 2
Paint 1
Domestic Mediumhair 1
Shih Tzu 1
Cattle (other) 1
Boxer (German Boxer) 1
American Shorthair 1

Associated Drugs

Carprofen 5
Maropitant Citrate 4
Gabapentin 4
Prednisone 3
Bedinvetmab 3
Dexmedetomidine 3
Manuka Honey 3
Enrofloxacin 2
Robenacoxib 2
Diphenhydramine 2
Frunevetmab 2
Oclacitinib Maleate 2
Dd (Presumably Dexdomitor) 2
Tigilanol Tiglate 2
Butorphanol 2
Atipamezole 2
Enzymatic Ear Drops 2
Pentoxifylline 2
Cefpodoxime 2
4% Chlorhexidine Gluconate, Tris-Edta 2

Injection site skin scaling Reaction Insights

23 reports name Injection site skin scaling; 1 recorded a death outcome (4.3% of reported events, not a population-level mortality rate). VeDDRA code: 2203.

By species: Dog (13 reports), Cat (8 reports), Horse (1 reports). By breed: Domestic Shorthair (5), Chihuahua (2), Doberman Pinscher (2).

Most co-reported drugs: Carprofen (5 reports), Maropitant Citrate (4 reports), Gabapentin (4 reports), Prednisone (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.