Reaction profile

The FDA adverse-event record for injection site skin scaling

Name: Injection site skin scaling - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

24 FDA reports name injection site skin scaling, a lower-volume reaction in the CVM extract (VeDDRA 2203). Plate stamps and neighbourhood peers follow.

#2086 of 2,481
by report volume (all reactions): 24
reports citing this reaction: 4.2%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Injection site skin scaling has 24 reports now versus 24 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: −0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Injection site skin scaling changes

FDA AER · VeDDRA plate

Code 2203 VOL-TRACE

VOL-TRACE · DEATH-LOW · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 24 reports
DEATH-LOW 4.2%
LOWER-Q #2086/2481
PHOTO-FINISH Acute pancreatitis
SPECIES-DOG Dog · 14
DRUG-LEAD Carprofen · 5
DESK-WIDE 16 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Acute pancreatitis (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Injection site skin scaling

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Injection site skin scaling

Injection site skin scaling: low death-coded share in the FDA AER plate

Signature read: 1 death-coded reports is a thin tail count for Injection site skin scaling in the CVM extract. Report volume is lower-third scale: 24 named reports in the openFDA extract. Death-coded share is lower-third: 1 of 24 reports (4.2% of named reports). Nearest volume peer: Acute pancreatitis (±0 reports). Lead species Dog (14). Lead co-reported drug Carprofen (5).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Carprofen appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 14

Cat 8

Horse 1

Cattle 1

Breeds Most Affected

Domestic Shorthair 5

Chihuahua 3

Doberman Pinscher 2

Crossbred Canine/dog 2

Paint 1

Domestic Mediumhair 1

Shih Tzu 1

Cattle (other) 1

Boxer (German Boxer) 1

American Shorthair 1

Associated Drugs

Carprofen 5

Gabapentin 5

Maropitant Citrate 4

Prednisone 4

Bedinvetmab 3

Dexmedetomidine 3

Manuka Honey 3

Enrofloxacin 2

Melarsomine Dihydrochloride 2

Robenacoxib 2

Diphenhydramine 2

Frunevetmab 2

Oclacitinib Maleate 2

Dd (Presumably Dexdomitor) 2

Tigilanol Tiglate 2

Butorphanol 2

Atipamezole 2

Enzymatic Ear Drops 2

Pentoxifylline 2

Cefpodoxime 2

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Injection site skin scaling (#2086 of 2,481 by report volume); death-coded 4.2%. PlainBreed reaction plate · death-coded report count stamp 1 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →