Reaction profile

The FDA adverse-event record for lymphoedema

35 FDA reports name lymphoedema, a lower-volume reaction in the CVM extract (VeDDRA 2319). Plate stamps and neighbourhood peers follow.

#1923 of 2,481
by report volume (all reactions)
35
reports citing this reaction
25.7%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lymphoedema has 35 reports now versus 35 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
−0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lymphoedema changes

FDA AER · VeDDRA plate

Code 2319 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 35 reports
  • DEATH-HOT 25.7%
  • LOWER-Q #1923/2481
  • PHOTO-FINISH CARBON DIOXIDE LOW, B…
  • SPECIES-DOG Dog · 29
  • DRUG-LEAD Prednisone · 9
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: CARBON DIOXIDE LOW, BLOOD (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Lymphoedema

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348CARBON DIOXIDE LOW, B… · near35Cerebral oedema · near35Comedo/blackhead · near35Gastric torsion · near35Lymphoedema · this reaction35Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lymphoedema

Lymphoedema: high death-coded share in the FDA AER plate

Signature read: 35 reports place Lymphoedema in the lower third of FDA AER volume (#1923 of 2,481). Report volume is lower-third scale: 35 named reports in the openFDA extract. Death-coded share is upper-third: 9 of 35 reports (25.7% of named reports). Nearest volume peer: CARBON DIOXIDE LOW, BLOOD (±0 reports). Lead species Dog (29). Lead co-reported drug Prednisone (9).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 29
Cat 4
Cattle 2

Breeds Most Affected

Retriever - Labrador 5
Chihuahua 3
Domestic Shorthair 2
Terrier - Bull - Staffordshire 2
Shepherd Dog - German 2
Doberman Pinscher 2
Singapura 2
Bulldog - English 2
Terrier - Bull - American Pit 1
Poodle (unspecified) 1

Associated Drugs

Prednisone 9
Tigilanol Tiglate 8
Maropitant Citrate 7
Carprofen 6
Bedinvetmab 5
Oclacitinib Maleate 4
Diphenhydramine 4
Gabapentin 4
Robenacoxib 4
Anti-Il31 Mab Mcs Lot #1283563 3
Pimobendan 3
Canine Cough Syrup 3
Trazodone 3
Cefovecin 2
Fluralaner Chew Tablets 2
Fluralaner Spot-On Solution 2
Verdinexor 2
Unknown Manufacturer Furosemide 2
Butorphanol Tartrate 2
Galliprant 2

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lymphoedema (#1923 of 2,481 by report volume); death-coded 25.7%. PlainBreed reaction plate · report volume stamp 35 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →