Reaction profile

The FDA adverse-event record for paraplegia

55 FDA adverse-event reports reference paraplegia (VeDDRA 692). See the species, breeds, and drugs most associated with it below.

55
reports citing this reaction
41.8%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
55
Total Reports
23
Deaths
41.8%
Death Rate

Species Most Affected

Dog 43
Cat 10
Cattle 1
Pig 1

Breeds Most Affected

Domestic Shorthair 8
Siberian Husky 7
Retriever - Labrador 5
Shepherd Dog - German 3
Spaniel - Cocker American 2
Shepherd Dog - Australian 2
Retriever - Golden 2
Corgi - Welsh Pembroke 2
Crossbred Canine/dog 2
Cat (unknown) 1

Associated Drugs

Bedinvetmab 13
Gabapentin 10
Milbemycin Oxime + Spinosad 9
Carprofen 7
Clindamycin 4
Tramadol 3
Melarsomine Dihydrochloride 3
Fluralaner 13.64% 12-Week Chew 3
Pyrantel Pamoate;Sarolaner 3
Prednisone 3
Vitamin B12 3
Spinosad 2
Meloxicam 2
Cedarwood Oil/Lemongrass Oil 2
Oclacitinib Maleate 2
Isoflurane 2
Sarolaner 2
Maropitant Citrate 2
Afoxolaner 2
Fluralaner Spot-On Solution 2

Paraplegia Reaction Insights

55 reports name Paraplegia; 23 recorded a death outcome (41.8% of reported events, not a population-level mortality rate). VeDDRA code: 692.

By species: Dog (43 reports), Cat (10 reports), Cattle (1 reports). By breed: Domestic Shorthair (8), Siberian Husky (7), Retriever - Labrador (5).

Most co-reported drugs: Bedinvetmab (13 reports), Gabapentin (10 reports), Milbemycin Oxime + Spinosad (9 reports), Carprofen (7 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.