Reaction profile

The FDA adverse-event record for paraplegia

61 FDA adverse-event reports reference paraplegia (VeDDRA 692). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1650 of 2,481
by report volume (all reactions)
61
reports citing this reaction
42.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Paraplegia has 61 reports now versus 59 in that prior snapshot: 2 more (3.4%).

Report change
+2
Death-coded reports
+1
Death-coded share
+0.3 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Paraplegia changes

FDA AER · VeDDRA plate

Code 692 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 61 reports
  • DEATH-HOT 42.6%
  • MID-PACK #1650/2481
  • PHOTO-FINISH Injection site numbne…
  • SPECIES-DOG Dog · 48
  • DRUG-LEAD Bedinvetmab · 15
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Injection site numbness (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Report-volume neighbourhood around Paraplegia

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Injection site numbne… · near61Intussusception · near61Oral pain · near61Paraplegia · this reaction61Retinal haemorrhage · near61Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Paraplegia

Paraplegia: high death-coded share in the FDA AER plate

Signature read: Paraplegia's 42.6% death-coded share is among the highest in the openFDA reaction corpus. Report volume sits in the middle third of the reaction corpus. Death-coded share is upper-third: 26 of 61 reports (42.6% of named reports). Nearest volume peer: Injection site numbness (±0 reports). Lead species Dog (48). Lead co-reported drug Bedinvetmab (15).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 48
Cat 11
Cattle 1
Pig 1

Breeds Most Affected

Domestic Shorthair 8
Retriever - Labrador 7
Siberian Husky 6
Shepherd Dog - German 3
Spaniel - Cocker American 2
Shepherd Dog - Australian 2
Retriever - Golden 2
Corgi - Welsh Pembroke 2
Crossbred Canine/dog 2
Boxer (German Boxer) 2

Associated Drugs

Bedinvetmab 15
Gabapentin 11
Milbemycin Oxime + Spinosad 9
Carprofen 8
Prednisone 6
Clindamycin 4
Oclacitinib Maleate 4
Melarsomine Dihydrochloride 4
Tramadol 3
Fluralaner 13.64% 12-Week Chew 3
Pyrantel Pamoate;Sarolaner 3
Vitamin B12 3
Spinosad 2
Meloxicam 2
Cedarwood Oil/Lemongrass Oil 2
Ketamine 2
Isoflurane 2
Sarolaner 2
Maropitant Citrate 2
Afoxolaner 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Paraplegia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (61 here).

Similar death-coded share

Nearest other reactions by death-coded share (42.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Paraplegia (#1650 of 2,481 by report volume); death-coded 42.6%. PlainBreed reaction plate · death-coded share stamp 42.6% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →