Chewing disorder

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VeDDRA Code: 2449

62 adverse event reports referencing this reaction

62
Total Reports
7
Deaths
1130.0%
Death Rate

Species Most Affected

Dog 41
Cat 17
Horse 4

Breeds Most Affected

Cat (unknown) 7
Domestic Shorthair 7
Retriever - Labrador 5
Crossbred Canine/dog 4
Pit Bull 3
Shih Tzu 3
Chihuahua 3
Pekingese 2
Terrier - Bull - American Pit 2
Boxer (German Boxer) 1

Associated Drugs

Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 10
Carprofen 8
Maropitant Citrate 7
Pyrantel Pamoate;Sarolaner 6
Bedinvetmab 5
Milbemycin Oxime + Praziquantel 4
Prednisone 4
Buprenorphine 4
Afoxolaner 3
Spinosad 3
Milbemycin Oxime + Spinosad 3
Dexmedetomidine 3
Fluralaner 3
Sarolaner 2
Lotilaner 2
Gabapentin 2
Eprinomectin + Praziquantel 2
Antihistamines 2
Ear Cleaner 2
Pantoprazole 2

Data Summary

Metric Value
Total reports referencing reaction 62
Reports with fatal outcome 7
Case-fatality rate (reported events) 1130.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2449.

Chewing disorder Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 62 adverse event reports that reference Chewing disorder as a reaction term, including 7 reports with a death outcome — a 1130.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2449, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Chewing disorder appears most frequently in reports for Dog (41 reports), Cat (17 reports), Horse (4 reports) — with Dog dominating at 41 entries. Within those species, the breeds most often named alongside this reaction are Cat (unknown) (7), Domestic Shorthair (7), Retriever - Labrador (5). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Chewing disorder are Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride (10 reports), Carprofen (8 reports), Maropitant Citrate (7 reports), Pyrantel Pamoate;Sarolaner (6 reports), with Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride appearing alongside this reaction in 10 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial