Reaction profile

The FDA adverse-event record for blood chemistry abnormal

10 FDA reports name blood chemistry abnormal, a lower-volume reaction in the CVM extract (VeDDRA 99223). Plate stamps and neighbourhood peers follow.

#2446 of 2,481
by report volume (all reactions)
10
reports citing this reaction
10.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. BLOOD CHEMISTRY ABNORMAL has 10 reports now versus 10 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to BLOOD CHEMISTRY ABNORMAL changes

FDA AER · VeDDRA plate

Code 99223 VOL-TRACE

VOL-TRACE · DEATH-ELEV · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 10 reports
  • DEATH-ELEV 10.0%
  • BOTTOM-DECILE #2446/2481
  • PHOTO-FINISH Anoxia
  • SPECIES-DOG Dog · 9
  • DRUG-LEAD Ivermectin + Pyra… · 3
  • DESK-WIDE 10 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Anoxia (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around BLOOD CHEMISTRY ABNORMAL

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Anoxia · near10Blackout · near10BLOOD CHEMISTRY ABNOR… · thi…10Bronchial secretion · near10Congenital renal and… · near10Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around BLOOD CHEMISTRY ABNORMAL

What the FDA AER plate says about BLOOD CHEMISTRY ABNORMAL

Signature read: 10 reports place BLOOD CHEMISTRY ABNORMAL in the lower third of FDA AER volume (#2446 of 2,481). Report volume is lower-third scale: 10 named reports in the openFDA extract. 1 of 10 reports were death-coded (10.0% of named reports, not a population mortality rate). Nearest volume peer: Anoxia (±0 reports). Lead species Dog (9). Lead co-reported drug Ivermectin + Pyrantel (3).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Ivermectin + Pyrantel appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 9
Horse 1

Breeds Most Affected

Shepherd Dog - German 1
Basenji 1
Griffon - French Wire-haired Pointing 1
Terrier - Yorkshire 1
Bulldog 1
Retriever - Golden 1
Quarter Horse 1
Crossbred Canine/dog 1
Pit Bull 1
Retriever - Labrador 1

Associated Drugs

Ivermectin + Pyrantel 3
Levothyroxine Sodium 3
Phenylpropropanolamine Hcl 2
Meloxicam 1
Tramadol 1
Carprofen 1
Deslorelin 1
Phenylpropanolamine Hydrochloride 1
Unspecified Joint Supplements 1
Gabapentin 1
Multivitamin 1
Enrofloxacin 1
Amoxicillin 1
Liver Support Medication 1
Phenobarbital 1
Oral Electrolyte Solution 1
Levetiracetam 1
Unspecified Taurine 1
Afoxolaner 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for BLOOD CHEMISTRY ABNORMAL (#2446 of 2,481 by report volume); death-coded 10.0%. PlainBreed reaction plate · report volume stamp 10 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →