Reaction profile

The FDA adverse-event record for blood chemistry abnormal

10 FDA adverse-event reports reference blood chemistry abnormal (VeDDRA 99223). See the species, breeds, and drugs most associated with it below.

10
reports citing this reaction
10.0%
death-coded share
Dog
most-affected species
Ivermectin + Pyrantel
most-associated drug
Verify with FDA CVM →
10
Total Reports
1
Deaths
10.0%
Death Rate

Species Most Affected

Dog 9
Horse 1

Breeds Most Affected

Shepherd Dog - German 1
Basenji 1
Griffon - French Wire-haired Pointing 1
Bulldog 1
Terrier - Yorkshire 1
Retriever - Golden 1
Quarter Horse 1
Crossbred Canine/dog 1
Retriever - Labrador 1
Pit Bull 1

Associated Drugs

Ivermectin + Pyrantel 3
Levothyroxine Sodium 3
Phenylpropropanolamine Hcl 2
Meloxicam 1
Tramadol 1
Carprofen 1
Deslorelin 1
Phenylpropanolamine Hydrochloride 1
Afoxolaner 1
Unspecified Joint Supplements 1
Gabapentin 1
Multivitamin 1
Enrofloxacin 1
Amoxicillin 1
Liver Support Medication 1
Phenobarbital 1
Oral Electrolyte Solution 1
Levetiracetam 1
Unspecified Taurine 1

BLOOD CHEMISTRY ABNORMAL Reaction Insights

10 reports name BLOOD CHEMISTRY ABNORMAL; 1 recorded a death outcome (10.0% of reported events, not a population-level mortality rate). VeDDRA code: 99223.

By species: Dog (9 reports), Horse (1 reports). By breed: Shepherd Dog - German (1), Basenji (1), Griffon - French Wire-haired Pointing (1).

Most co-reported drugs: Ivermectin + Pyrantel (3 reports), Levothyroxine Sodium (3 reports), Phenylpropropanolamine Hcl (2 reports), Meloxicam (1 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.