Dysorexia

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VeDDRA Code: 2271

26 adverse event reports referencing this reaction

26
Total Reports
1
Deaths
380.0%
Death Rate

Species Most Affected

Dog 22
Cat 3
Horse 1

Breeds Most Affected

Domestic Shorthair 3
Chihuahua 2
Terrier - Jack Russell 2
Beagle 2
Shih Tzu 2
Terrier - Yorkshire 2
Terrier - Bull - Staffordshire 1
Horse (unknown) 1
Retriever - Labrador 1
Collie (unspecified) 1

Associated Drugs

Trilostane 12
Prednisone 3
Carprofen 2
Milbemycin Oxime + Spinosad 2
Desoxycortone Pivalate 2
Verdinexor 2
Pimobendan 2
Amlodipine 2
Ivermectin 1
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 1
Firocoxib 1
Polysulfated Glycosaminoglycan 1
Ivermectin 10 Mg/Ml Solution For Injection 1
Afoxolaner 68 Mg Chewable Tablets 1
Levothyroxine Sodium 1
Phenylpropropanolamine Hcl 1
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 1
Ear Cleaner (Unknown) 1
Lokivetmab Injectable Solution 1
Cefovecin Sodium 1

Data Summary

Metric Value
Total reports referencing reaction 26
Reports with fatal outcome 1
Case-fatality rate (reported events) 380.0%
Species observed 3
Breeds observed 19
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2271.

Dysorexia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 26 adverse event reports that reference Dysorexia as a reaction term, including 1 reports with a death outcome — a 380.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2271, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Dysorexia appears most frequently in reports for Dog (22 reports), Cat (3 reports), Horse (1 reports) — with Dog dominating at 22 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (3), Chihuahua (2), Terrier - Jack Russell (2). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Dysorexia are Trilostane (12 reports), Prednisone (3 reports), Carprofen (2 reports), Milbemycin Oxime + Spinosad (2 reports), with Trilostane appearing alongside this reaction in 12 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial