Urinary tract infection

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VeDDRA Code: 2026

4,317 adverse event reports referencing this reaction

4,317
Total Reports
523
Deaths
1210.0%
Death Rate

Species Most Affected

Dog 3,762
Cat 551
Human 2
Horse 1
Ferret 1

Breeds Most Affected

Retriever - Labrador 507
Domestic Shorthair 344
Crossbred Canine/dog 247
Retriever - Golden 146
Shepherd Dog - German 126
Dog (unknown) 123
Boxer (German Boxer) 121
Shih Tzu 108
Terrier - Yorkshire 99
Beagle 97

Associated Drugs

Bedinvetmab 864
Trilostane 841
Oclacitinib Maleate 390
Milbemycin Oxime + Spinosad 374
Carprofen 301
Gabapentin 270
Maropitant Citrate 167
Milbemycin Oxime + Praziquantel 157
Prednisone 139
Afoxolaner 138
Grapiprant 122
Fluralaner Chew Tablets 112
Enrofloxacin 110
Velagliflozin Proline Monohydrate 99
Bexagliflozin 97
Spinosad 94
Cyclosporine 93
Moxidectin 89
Ivermectin + Pyrantel As Pamoate Salt 86
Frunevetmab 86

Data Summary

Metric Value
Total reports referencing reaction 4,317
Reports with fatal outcome 523
Case-fatality rate (reported events) 1210.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2026.

Urinary tract infection Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 4,317 adverse event reports that reference Urinary tract infection as a reaction term, including 523 reports with a death outcome — a 1210.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2026, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Urinary tract infection appears most frequently in reports for Dog (3,762 reports), Cat (551 reports), Human (2 reports) — with Dog dominating at 3,762 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (507), Domestic Shorthair (344), Crossbred Canine/dog (247). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Urinary tract infection are Bedinvetmab (864 reports), Trilostane (841 reports), Oclacitinib Maleate (390 reports), Milbemycin Oxime + Spinosad (374 reports), with Bedinvetmab appearing alongside this reaction in 864 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial