Septicaemia

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VeDDRA Code: 1035

467 adverse event reports referencing this reaction

467
Total Reports
350
Deaths
7490.0%
Death Rate

Species Most Affected

Dog 353
Cattle 48
Cat 34
Horse 10
Chicken 7
Pig 7
Human 2
Turtle 1
Other Rodents 1
Other Deer 1

Breeds Most Affected

Retriever - Labrador 71
Holstein-Friesian also known as Holstein 22
Shepherd Dog - German 19
Rottweiler 19
Domestic Shorthair 19
Retriever - Golden 13
Boxer (German Boxer) 13
Mastiff 10
Crossbred Canine/dog 10
Terrier - Yorkshire 10

Associated Drugs

Carprofen 86
Maropitant Citrate 81
Deracoxib 47
Enrofloxacin 42
Meloxicam 39
Gabapentin 38
Buprenorphine 35
Tramadol 26
Isoflurane 26
Firocoxib 25
Propofol 22
Oclacitinib Maleate 21
Famotidine 19
Metronidazole 18
Midazolam 18
Metoclopramide 17
Fentanyl 17
Ondansetron 16
Maropitant 15
Cefovecin 15

Data Summary

Metric Value
Total reports referencing reaction 467
Reports with fatal outcome 350
Case-fatality rate (reported events) 7490.0%
Species observed 10
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1035.

Septicaemia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 467 adverse event reports that reference Septicaemia as a reaction term, including 350 reports with a death outcome — a 7490.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1035, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Septicaemia appears most frequently in reports for Dog (353 reports), Cattle (48 reports), Cat (34 reports) — with Dog dominating at 353 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (71), Holstein-Friesian also known as Holstein (22), Shepherd Dog - German (19). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Septicaemia are Carprofen (86 reports), Maropitant Citrate (81 reports), Deracoxib (47 reports), Enrofloxacin (42 reports), with Carprofen appearing alongside this reaction in 86 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial