Reaction profile

The FDA adverse-event record for increased percentage reticulocytes

983 FDA reports name increased percentage reticulocytes, a high-volume reaction in the CVM extract (VeDDRA 2213). Plate stamps and neighbourhood peers follow.

#399 of 2,481
by report volume (all reactions)
983
reports citing this reaction
26.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Increased percentage reticulocytes has 983 reports now versus 944 in that prior snapshot: 39 more (4.1%).

Report change
+39
Death-coded reports
+5
Death-coded share
−0.5 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Increased percentage reticulocytes changes

FDA AER · VeDDRA plate

Code 2213 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 983 reports
  • DEATH-HOT 26.0%
  • UPPER-Q #399/2481
  • PHOTO-FINISH Stopper, abnormal
  • SPECIES-DOG Dog · 866
  • DRUG-LEAD Carprofen · 120
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Stopper, abnormal (±1 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Increased percentage reticulocytes

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Lack of efficacy (tap… · near990Stopper, abnormal · near984Increased percentage… · this…983Jaundice · near980Abnormal movement NOS · near978Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Increased percentage reticulocytes

Increased percentage reticulocytes: high death-coded share in the FDA AER plate

Signature read: 256 death-coded reports is a heavy tail count for Increased percentage reticulocytes in the CVM extract. Report volume is upper-third scale: 983 named reports in the openFDA extract. Death-coded share is upper-third: 256 of 983 reports (26.0% of named reports). Nearest volume peer: Stopper, abnormal (±1 reports). Lead species Dog (866). Lead co-reported drug Carprofen (120).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 866
Cat 117

Breeds Most Affected

Retriever - Labrador 83
Crossbred Canine/dog 74
Domestic Shorthair 73
Chihuahua 41
Retriever - Golden 40
Shepherd Dog - German 32
Shih Tzu 30
Terrier - Yorkshire 26
Boxer (German Boxer) 22
Beagle 21

Associated Drugs

Carprofen 120
Maropitant Citrate 112
Afoxolaner 76
Oclacitinib Maleate 74
Prednisone 70
Trilostane 67
Gabapentin 58
Moxidectin 51
Fluralaner Chew Tablets 50
Ivermectin + Pyrantel As Pamoate Salt 49
Milbemycin Oxime + Spinosad 47
Bedinvetmab 46
Doxycycline 44
Metronidazole 39
Cyclosporine 38
Enrofloxacin 37
Fluralaner 13.64% 12-Week Chew 37
Rabies Vaccine 36
Grapiprant 35
Cefovecin 30

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Increased percentage reticulocytes, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (983 here).

Similar death-coded share

Nearest other reactions by death-coded share (26.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Increased percentage reticulocytes (#399 of 2,481 by report volume); death-coded 26.0%. PlainBreed reaction plate · death-coded report count stamp 256 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →