Reaction profile

The FDA adverse-event record for elevated red cell distribution width (rdw)

55 FDA reports name elevated red cell distribution width (rdw), a lower-volume reaction in the CVM extract (VeDDRA 2857). Plate stamps and neighbourhood peers follow.

#1691 of 2,481
by report volume (all reactions)
55
reports citing this reaction
36.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Elevated red cell distribution width (RDW) has 55 reports now versus 51 in that prior snapshot: 4 more (7.8%).

Report change
+4
Death-coded reports
+1
Death-coded share
−0.9 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Elevated red cell distribution width (RDW) changes

FDA AER · VeDDRA plate

Code 2857 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 55 reports
  • DEATH-HOT 36.4%
  • MID-PACK #1691/2481
  • PHOTO-FINISH Central nervous syste…
  • SPECIES-DOG Dog · 32
  • DRUG-LEAD Maropitant Citrate · 8
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Central nervous system depression (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Elevated red cell distribution width

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Central nervous syste… · near55Elevated red cell dis… · thi…55Insert, Abnormal · near55Oral abscess · near55Oral haemorrhage · near55Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Elevated red cell distribution width (RDW)

Elevated red cell distribution width (RDW): high death-coded share in the FDA AER plate

Signature read: Elevated red cell distribution width (RDW)'s 36.4% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 55 named reports in the openFDA extract. Death-coded share is upper-third: 20 of 55 reports (36.4% of named reports). Nearest volume peer: Central nervous system depression (±0 reports). Lead species Dog (32). Lead co-reported drug Maropitant Citrate (8).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 32
Cat 22
Horse 1

Breeds Most Affected

Domestic Shorthair 14
Retriever - Labrador 6
Domestic Longhair 3
Bulldog - French 3
Crossbred Canine/dog 3
Shepherd Dog - German 2
Terrier - Bull - Staffordshire 2
Dog (other) 2
Doberman Pinscher 2
Spitz - German Pomeranian 1

Associated Drugs

Maropitant Citrate 8
Buprenorphine 8
Eprinomectin + Esafoxolaner + Praziquantel 6
Carprofen 5
Lotilaner 5
Ampicillin Sodium/Sulbactam Sodium 5
Propofol 4
Bedinvetmab 4
Rabies Vaccine 4
Ilunocitinib 4
Fluid Therapy 4
Metronidazole 4
Dexamethasone Sodium Phosphate 4
Robenacoxib 3
Purevax Feline 3/Rabies - 16T9.R0 3
Purevax Recombinant Felv - 1555.R4 3
Capromorelin 3
Prednisone 3
Lotilaner,Moxidectin,Praziquantel,Pyrantel Pamoate 3
Pantoprazole 3

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Elevated red cell distribution width (RDW), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (55 here).

Similar death-coded share

Nearest other reactions by death-coded share (36.4% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Elevated red cell distribution width (RDW) (#1691 of 2,481 by report volume); death-coded 36.4%. PlainBreed reaction plate · death-coded share stamp 36.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →