Reaction profile

The FDA adverse-event record for tongue necrosis

37 FDA adverse-event reports reference tongue necrosis (VeDDRA 1980). See the species, breeds, and drugs most associated with it below.

37
reports citing this reaction
37.8%
death-coded share
Dog
most-affected species
Meloxicam
most-associated drug
Verify with FDA CVM →
37
Total Reports
14
Deaths
37.8%
Death Rate

Species Most Affected

Dog 28
Cat 6
Horse 3

Breeds Most Affected

Dog (unknown) 3
Domestic Shorthair 2
Retriever - Labrador 2
Chihuahua 2
Shepherd Dog - Australian 2
Maltese 2
Terrier - Bedlington 2
Pit Bull 2
Terrier - Yorkshire 2
Terrier - Fox Wire 1

Associated Drugs

Meloxicam 5
Buprenorphine 5
Carprofen 4
Isoflurane 4
Tigilanol Tiglate 4
Prednisone 3
Oclacitinib Maleate 3
Trilostane 2
Spinosad 2
Tramadol 2
Maropitant Citrate 2
Famotidine 2
Nitenpyram 2
Afoxolaner 2
Deracoxib 2
Vaccine 2
Butorphanol 2
Anesthetic (Unknown) 2
Hydromorphone 2
Propofol 2

Tongue necrosis Reaction Insights

37 reports name Tongue necrosis; 14 recorded a death outcome (37.8% of reported events, not a population-level mortality rate). VeDDRA code: 1980.

By species: Dog (28 reports), Cat (6 reports), Horse (3 reports). By breed: Dog (unknown) (3), Domestic Shorthair (2), Retriever - Labrador (2).

Most co-reported drugs: Meloxicam (5 reports), Buprenorphine (5 reports), Carprofen (4 reports), Isoflurane (4 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.