Reaction profile

The FDA adverse-event record for jaw disorder

368 FDA reports name jaw disorder, a high-volume reaction in the CVM extract (VeDDRA 600). Plate stamps and neighbourhood peers follow.

#778 of 2,481
by report volume (all reactions)
368
reports citing this reaction
14.4%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Jaw disorder has 368 reports now versus 363 in that prior snapshot: 5 more (1.4%).

Report change
+5
Death-coded reports
+1
Death-coded share
+0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Jaw disorder changes

FDA AER · VeDDRA plate

Code 600 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 368 reports
  • DEATH-ELEV 14.4%
  • MID-PACK #778/2481
  • PHOTO-FINISH Abdominal cavity haem…
  • SPECIES-DOG Dog · 320
  • DRUG-LEAD Milbemycin Oxime… · 62
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Abdominal cavity haemorrhage (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Jaw disorder

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Abdominal cavity haem… · near368Jaw disorder · this reaction368Lot # and/or Expirati… · near368Prolonged activated p… · near368Administration device… · near367Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Jaw disorder

What the FDA AER plate says about Jaw disorder

Signature read: 53 death-coded reports is a heavy tail count for Jaw disorder in the CVM extract. Report volume is upper-third scale: 368 named reports in the openFDA extract. 53 of 368 reports were death-coded (14.4% of named reports, not a population mortality rate). Nearest volume peer: Abdominal cavity haemorrhage (±0 reports). Lead species Dog (320). Lead co-reported drug Milbemycin Oxime + Spinosad (62).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 320
Cat 33
Cattle 5
Horse 4
Human 2
Donkey 2
Ferret 1
Deer 1

Breeds Most Affected

Retriever - Labrador 37
Crossbred Canine/dog 33
Domestic Shorthair 21
Retriever - Golden 17
Terrier - Yorkshire 14
Chihuahua 10
Beagle 9
Pit Bull 9
Shepherd Dog - German 8
Shih Tzu 8

Associated Drugs

Milbemycin Oxime + Spinosad 62
Afoxolaner 28
Pyrantel Pamoate;Sarolaner 24
Fluralaner Chew Tablets 21
Maropitant Citrate 20
Carprofen 19
Fluralaner 13.64% 12-Week Chew 19
Sarolaner 18
Gabapentin 16
Oclacitinib Maleate 15
Bedinvetmab 15
Ivermectin + Pyrantel As Pamoate Salt 14
Milbemycin Oxime + Praziquantel 12
Spinosad 11
Enrofloxacin 10
Buprenorphine 10
Trilostane 10
Moxidectin 9
Prednisone 8
Imidacloprid + Moxidectin 8

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Jaw disorder, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Jaw disorder (#778 of 2,481 by report volume); death-coded 14.4%. PlainBreed reaction plate · death-coded report count stamp 53 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →