Reaction profile

The FDA adverse-event record for alopecia

1,797 FDA reports name alopecia, a high-volume reaction in the CVM extract (VeDDRA 1309). Plate stamps and neighbourhood peers follow.

#254 of 2,481
by report volume (all reactions)
1,797
reports citing this reaction
4.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Alopecia has 1,797 reports now versus 1,777 in that prior snapshot: 20 more (1.1%).

Report change
+20
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Alopecia changes

FDA AER · VeDDRA plate

Code 1309 VOL-MID

VOL-MID · DEATH-LOW · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,797 reports
  • DEATH-LOW 4.6%
  • UPPER-Q #254/2481
  • PHOTO-FINISH Decreased packed cell…
  • SPECIES-DOG Dog · 1,166
  • DRUG-LEAD Frunevetmab · 225
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Decreased packed cell volume (PCV) (±17 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Alopecia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Hypochloraemia · near1824Hyponatremia · near1822Decreased packed cell… · near1814Alopecia · this reaction1797Neoplasia NOS · near1770Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Alopecia

Alopecia: low death-coded share in the FDA AER plate

Signature read: 1,797 reports place Alopecia in the upper third of FDA AER volume (#254 of 2,481). Report volume is upper-third scale: 1,797 named reports in the openFDA extract. Death-coded share is lower-third: 83 of 1,797 reports (4.6% of named reports). Nearest volume peer: Decreased packed cell volume (PCV) (±17 reports). Lead species Dog (1,166). Lead co-reported drug Frunevetmab (225).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Frunevetmab appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,166
Cat 540
Cattle 69
Horse 15
Ferret 2
Human 1
Mouse 1
Rat 1
Hedgehog 1
Lynx 1

Breeds Most Affected

Domestic Shorthair 342
Retriever - Labrador 165
Crossbred Canine/dog 76
Chihuahua 57
Pit Bull 54
Shepherd Dog - German 52
Retriever - Golden 51
Domestic Longhair 47
Boxer (German Boxer) 40
Dog (unknown) 39

Associated Drugs

Frunevetmab 225
Milbemycin Oxime + Spinosad 174
Oclacitinib Maleate 130
Trilostane 115
Afoxolaner 111
Selamectin 110
Imidacloprid + Moxidectin 86
Moxidectin 77
Fluralaner Chew Tablets 76
Prednisone 68
Cefovecin 66
Spinosad 65
Selamectin;Sarolaner 51
Fluralaner Spot-On Solution 47
Bedinvetmab 46
Anti-Il31 Mab Mcs Lot #1283563 44
Gabapentin 40
Rabacfosadine Succinate 40
Pyrantel Pamoate;Sarolaner 36
Carprofen 35

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Alopecia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (1,797 here).

Similar death-coded share

Nearest other reactions by death-coded share (4.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Alopecia (#254 of 2,481 by report volume); death-coded 4.6%. PlainBreed reaction plate · report volume stamp 1,797 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →