Hypocalcaemic condition

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VeDDRA Code: 560

612 adverse event reports referencing this reaction

612
Total Reports
247
Deaths
4040.0%
Death Rate

Species Most Affected

Dog 479
Cat 99
Horse 17
Cattle 16
Goat 1

Breeds Most Affected

Domestic Shorthair 55
Retriever - Labrador 50
Terrier - Yorkshire 48
Crossbred Canine/dog 35
Chihuahua 26
Domestic (unspecified) 17
Dachshund (unspecified) 16
Maltese 16
Shih Tzu 15
Terrier - Boston 14

Associated Drugs

Carprofen 71
Maropitant Citrate 69
Milbemycin Oxime + Spinosad 55
Spinosad 51
Meloxicam 44
Oclacitinib Maleate 43
Fluralaner Chew Tablets 37
Cefovecin 29
Afoxolaner 29
Trilostane 28
Tramadol 21
Moxidectin 20
Prednisone 20
Famotidine 20
Metronidazole 19
Deracoxib 18
Enrofloxacin 18
Sucralfate 16
Diphenhydramine Hcl 16
Ivermectin + Pyrantel As Pamoate Salt 16

Data Summary

Metric Value
Total reports referencing reaction 612
Reports with fatal outcome 247
Case-fatality rate (reported events) 4040.0%
Species observed 5
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 560.

Hypocalcaemic condition Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 612 adverse event reports that reference Hypocalcaemic condition as a reaction term, including 247 reports with a death outcome — a 4040.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 560, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Hypocalcaemic condition appears most frequently in reports for Dog (479 reports), Cat (99 reports), Horse (17 reports) — with Dog dominating at 479 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (55), Retriever - Labrador (50), Terrier - Yorkshire (48). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Hypocalcaemic condition are Carprofen (71 reports), Maropitant Citrate (69 reports), Milbemycin Oxime + Spinosad (55 reports), Spinosad (51 reports), with Carprofen appearing alongside this reaction in 71 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial