Reaction profile

The FDA adverse-event record for hypocalcaemic condition

612 FDA adverse-event reports reference hypocalcaemic condition (VeDDRA 560). See the species, breeds, and drugs most associated with it below.

612
reports citing this reaction
40.4%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
612
Total Reports
247
Deaths
40.4%
Death Rate

Species Most Affected

Dog 479
Cat 99
Horse 17
Cattle 16
Goat 1

Breeds Most Affected

Domestic Shorthair 55
Retriever - Labrador 50
Terrier - Yorkshire 48
Crossbred Canine/dog 35
Chihuahua 26
Domestic (unspecified) 17
Dachshund (unspecified) 16
Maltese 16
Shih Tzu 15
Terrier - Boston 14

Associated Drugs

Carprofen 71
Maropitant Citrate 69
Milbemycin Oxime + Spinosad 55
Spinosad 51
Meloxicam 44
Oclacitinib Maleate 43
Fluralaner Chew Tablets 37
Cefovecin 29
Afoxolaner 29
Trilostane 28
Tramadol 21
Moxidectin 20
Prednisone 20
Famotidine 20
Metronidazole 19
Deracoxib 18
Enrofloxacin 18
Sucralfate 16
Diphenhydramine Hcl 16
Ivermectin + Pyrantel As Pamoate Salt 16

Hypocalcaemic condition Reaction Insights

612 reports name Hypocalcaemic condition; 247 recorded a death outcome (40.4% of reported events, not a population-level mortality rate). VeDDRA code: 560.

By species: Dog (479 reports), Cat (99 reports), Horse (17 reports). By breed: Domestic Shorthair (55), Retriever - Labrador (50), Terrier - Yorkshire (48).

Most co-reported drugs: Carprofen (71 reports), Maropitant Citrate (69 reports), Milbemycin Oxime + Spinosad (55 reports), Spinosad (51 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.