Reaction profile

The FDA adverse-event record for lack of coordination (see also 'ear' - vestibular disorder)

233 FDA adverse-event reports reference lack of coordination (see also 'ear' - vestibular disorder) (VeDDRA 656). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#969 of 2,481
by report volume (all reactions)
233
reports citing this reaction
12.0%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Lack of coordination (see also 'Ear' - vestibular disorder) has 142 reports now versus 142 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Lack of coordination (see also 'Ear' - vestibular disorder) changes

FDA AER · VeDDRA plate

Code 656 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 233 reports
  • DEATH-ELEV 12.0%
  • MID-PACK #969/2481
  • PHOTO-FINISH Local erythema
  • SPECIES-DOG Dog · 115
  • DRUG-LEAD Milbemycin Oxime… · 23
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Local erythema (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Lack of coordination

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Brain disorder NOS · near234Metastatic neoplasia · near234Lack of coordination… · this…233Local erythema · near233Ulcerative dermatitis · near233Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Lack of coordination (see also 'Ear' - vestibular disorder)

What the FDA AER plate says about Lack of coordination (see also 'Ear' - vestibular disorder)

Signature read: report volume at 233 (#969 of 2,481) is the standout scale stamp on Lack of coordination (see also 'Ear' - vestibular disorder). Report volume sits in the middle third of the reaction corpus. 28 of 233 reports were death-coded (12.0% of named reports, not a population mortality rate). Nearest volume peer: Local erythema (±0 reports). Lead species Dog (115). Lead co-reported drug Milbemycin Oxime + Spinosad (23).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 115
Cat 24
Cattle 2
Human 1

Breeds Most Affected

Domestic Shorthair 13
Crossbred Canine/dog 11
Retriever - Labrador 11
Shepherd Dog - Australian 6
Terrier - Yorkshire 5
Shepherd Dog - German 5
Chihuahua 5
Pug 4
Terrier - Jack Russell 4
Dog (unknown) 4

Associated Drugs

Milbemycin Oxime + Spinosad 23
Ivermectin + Pyrantel As Pamoate Salt 12
Afoxolaner 10
Pyrantel Pamoate;Sarolaner 9
Spinosad 8
Carprofen 8
Sarolaner 8
Ivermectin 7
Cefovecin 5
Maropitant Citrate 5
Selamectin 5
Fluralaner 13.64% 12-Week Chew 5
Fluralaner Chew Tablets 4
Nitenpyram 4
Ear Cleaner 4
Anesthetic 3
Isoflurane 3
Milbemycin Oxime 3
Grapiprant 3
Benzoyl Peroxide Shampoo 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Lack of coordination (see also 'Ear' - vestibular disorder), both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (233 here).

Similar death-coded share

Nearest other reactions by death-coded share (12.0% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Lack of coordination (see also 'Ear' - vestibular disorder) (#969 of 2,481 by report volume); death-coded 12.0%. PlainBreed reaction plate · report volume stamp 233 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →