Reaction profile

The FDA adverse-event record for ectropion

Name: Ectropion - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

10 FDA reports name ectropion, a lower-volume reaction in the CVM extract (VeDDRA 424). Plate stamps and neighbourhood peers follow.

#2453 of 2,481
by report volume (all reactions): 10
reports citing this reaction: 10.0%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

FDA AER · VeDDRA plate

Code 424 VOL-TRACE

VOL-TRACE · DEATH-ELEV · BOTTOM-DECILE · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 10 reports
DEATH-ELEV 10.0%
BOTTOM-DECILE #2453/2481
PHOTO-FINISH Anoxia
SPECIES-DOG Dog · 10
DRUG-LEAD Milbemycin Oxime… · 6
DESK-WIDE 10 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Anoxia (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Ectropion

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Ectropion

What the FDA AER plate says about Ectropion

Signature read: 10 reports place Ectropion in the lower third of FDA AER volume (#2453 of 2,481). Report volume is lower-third scale: 10 named reports in the openFDA extract. 1 of 10 reports were death-coded (10.0% of named reports, not a population mortality rate). Nearest volume peer: Anoxia (±0 reports). Lead species Dog (10). Lead co-reported drug Milbemycin Oxime + Spinosad (6).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Milbemycin Oxime + Spinosad appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 10

Breeds Most Affected

Bloodhound 1

Weimaraner 1

Boxer (German Boxer) 1

Mastiff - Neapolitan 1

Terrier - Bull 1

Deutsche Dogge, Great Dane 1

Shepherd Dog - German 1

American Pit Bull Terrier 1

Retriever - Labrador 1

Retriever - Golden 1

Associated Drugs

Milbemycin Oxime + Spinosad 6

Afoxolaner 68 Mg Chewable Tablets 2

Carprofen 2

Canine Distemper-Adenovirus Type 2-Parvovirus Vaccine, Modified Live Virus, Leptospira Canicola-Grippotyphosa-Icterohaemorrhagiae-Pomona Bacterial Extract 1

Rabies Vaccine, Killed Virus 1

Praziquantel + Pyrantel Pamoate + Febantel 1

Afoxolaner 1

Gabapentin 1

Trazodone 1

Cephalexin 1

Pyrantel Pamoate;Sarolaner 1

Florfenicol, Terbinafine, Betamethasone Acetate 1

Amoxicillin Trihydrate, Potassium Clavulanate 1

0.15% Ketoconazole In Usp Trizedta 1

Gentamicin Sulfate, Usp; Mometasone Furoate Anhydrous, Usp; Clotrimazole, Usp 1

Gentamicin Sulfate + Hydrocortisone Aceponate + Miconazole Nitrate 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ectropion (#2453 of 2,481 by report volume); death-coded 10.0%. PlainBreed reaction plate · report volume stamp 10 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →