Reaction profile

The FDA adverse-event record for atrial fibrillation

57 FDA reports name atrial fibrillation, a lower-volume reaction in the CVM extract (VeDDRA 187). Plate stamps and neighbourhood peers follow.

#1671 of 2,481
by report volume (all reactions)
57
reports citing this reaction
29.8%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Atrial fibrillation has 57 reports now versus 54 in that prior snapshot: 3 more (5.6%).

Report change
+3
Death-coded reports
+0
Death-coded share
−1.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Atrial fibrillation changes

FDA AER · VeDDRA plate

Code 187 VOL-LOW

VOL-LOW · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 57 reports
  • DEATH-HOT 29.8%
  • MID-PACK #1671/2481
  • PHOTO-FINISH Epistaxis (unilateral)
  • SPECIES-DOG Dog · 39
  • DRUG-LEAD Pimobendan · 9
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Epistaxis (unilateral) (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Atrial fibrillation

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Atrial fibrillation · this r…57Epistaxis (unilateral) · near57Eyelid lump · near57Lack of efficacy (bac… · near57Leucocytosis · near57Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Atrial fibrillation

Atrial fibrillation: high death-coded share in the FDA AER plate

Signature read: Atrial fibrillation's 29.8% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 57 named reports in the openFDA extract. Death-coded share is upper-third: 17 of 57 reports (29.8% of named reports). Nearest volume peer: Epistaxis (unilateral) (±0 reports). Lead species Dog (39). Lead co-reported drug Pimobendan (9).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 39
Horse 9
Cat 6
Human 2
Goat 1

Breeds Most Affected

Crossbred Canine/dog 7
Boxer (German Boxer) 3
Unknown 3
Domestic Shorthair 3
Quarter Horse 3
Deutsche Dogge, Great Dane 2
Domestic (unspecified) 2
Shepherd Dog - German 2
Retriever - Labrador 2
Thoroughbred 2

Associated Drugs

Pimobendan 9
Furosemide 4
Deracoxib 3
Trilostane 3
Milbemycin Oxime + Spinosad 3
Enalapril 3
Detomidine Hydrochloride 3
Benazepril 3
Isoflurane 3
Acepromazine 3
Carprofen 3
Fluoxetine 3
Maropitant 2
Dexmedetomidine Hydrochloride 2
Spinosad 2
Pentobarbital, Phenytoin 2
Diphenhydramine Hcl 2
Desoxycortone 2
Tramadol 2
Grapiprant 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Atrial fibrillation, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (29.8% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Atrial fibrillation (#1671 of 2,481 by report volume); death-coded 29.8%. PlainBreed reaction plate · death-coded share stamp 29.8% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →