Reaction profile

The FDA adverse-event record for pulmonary thromboembolism

100 FDA adverse-event reports reference pulmonary thromboembolism (VeDDRA 851). See the species, breeds, and drugs most associated with it below.

100
reports citing this reaction
53.0%
death-coded share
Dog
most-affected species
Melarsomine Dihydrochloride
most-associated drug
Verify with FDA CVM →
100
Total Reports
53
Deaths
53.0%
Death Rate

Species Most Affected

Dog 90
Cat 8
Horse 1
Unknown 1

Breeds Most Affected

Domestic Shorthair 6
Retriever - Labrador 6
Dog (unknown) 6
Chihuahua 5
Beagle 4
Dachshund (unspecified) 4
Crossbred Canine/dog 4
Terrier - Yorkshire 4
Unknown 4
Shepherd Dog - Australian 3

Associated Drugs

Melarsomine Dihydrochloride 19
Melarsomine Dihydrochloride Injection 18
Maropitant Citrate 9
Prednisone 9
Doxycycline 8
Ivermectin + Pyrantel As Pamoate Salt 7
Moxidectin 7
Milbemycin Oxime + Spinosad 6
Gabapentin 6
Trilostane 5
Spinosad 4
Milbemycin Oxime 3
Hydromorphone Hcl 3
Afoxolaner 3
Butorphanol 3
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 3
Imidacloprid + Moxidectin 2
Carprofen 2
Famotidine 2
Meloxicam 2

Pulmonary thromboembolism Reaction Insights

100 reports name Pulmonary thromboembolism; 53 recorded a death outcome (53.0% of reported events, not a population-level mortality rate). VeDDRA code: 851.

By species: Dog (90 reports), Cat (8 reports), Horse (1 reports). By breed: Domestic Shorthair (6), Retriever - Labrador (6), Dog (unknown) (6).

Most co-reported drugs: Melarsomine Dihydrochloride (19 reports), Melarsomine Dihydrochloride Injection (18 reports), Maropitant Citrate (9 reports), Prednisone (9 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.