Pulmonary thromboembolism

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VeDDRA Code: 851

100 adverse event reports referencing this reaction

100
Total Reports
53
Deaths
5300.0%
Death Rate

Species Most Affected

Dog 90
Cat 8
Horse 1
Unknown 1

Breeds Most Affected

Domestic Shorthair 6
Retriever - Labrador 6
Dog (unknown) 6
Chihuahua 5
Beagle 4
Dachshund (unspecified) 4
Crossbred Canine/dog 4
Terrier - Yorkshire 4
Unknown 4
Shepherd Dog - Australian 3

Associated Drugs

Melarsomine Dihydrochloride 19
Melarsomine Dihydrochloride Injection 18
Maropitant Citrate 9
Prednisone 9
Doxycycline 8
Ivermectin + Pyrantel As Pamoate Salt 7
Moxidectin 7
Milbemycin Oxime + Spinosad 6
Gabapentin 6
Trilostane 5
Spinosad 4
Milbemycin Oxime 3
Hydromorphone Hcl 3
Afoxolaner 3
Butorphanol 3
Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 3
Imidacloprid + Moxidectin 2
Carprofen 2
Famotidine 2
Meloxicam 2

Data Summary

Metric Value
Total reports referencing reaction 100
Reports with fatal outcome 53
Case-fatality rate (reported events) 5300.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 851.

Pulmonary thromboembolism Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 100 adverse event reports that reference Pulmonary thromboembolism as a reaction term, including 53 reports with a death outcome — a 5300.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 851, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Pulmonary thromboembolism appears most frequently in reports for Dog (90 reports), Cat (8 reports), Horse (1 reports) — with Dog dominating at 90 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (6), Retriever - Labrador (6), Dog (unknown) (6). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Pulmonary thromboembolism are Melarsomine Dihydrochloride (19 reports), Melarsomine Dihydrochloride Injection (18 reports), Maropitant Citrate (9 reports), Prednisone (9 reports), with Melarsomine Dihydrochloride appearing alongside this reaction in 19 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial