Hypermetria

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VeDDRA Code: 662

194 adverse event reports referencing this reaction

194
Total Reports
27
Deaths
1390.0%
Death Rate

Species Most Affected

Dog 171
Cat 17
Horse 5
Goat 1

Breeds Most Affected

Retriever - Labrador 17
Chihuahua 15
Domestic Shorthair 14
Retriever - Golden 10
Shepherd Dog - Australian 9
Crossbred Canine/dog 8
Terrier - Yorkshire 7
Maltese 7
Terrier - Jack Russell 6
Shepherd Dog - German 6

Associated Drugs

Milbemycin Oxime + Spinosad 25
Bedinvetmab 21
Afoxolaner 19
Gabapentin 16
Spinosad 12
Carprofen 12
Fluralaner Chew Tablets 12
Sarolaner 11
Maropitant Citrate 9
Pyrantel Pamoate;Sarolaner 9
Ivermectin 8
Moxidectin 7
Selamectin 7
Frunevetmab 7
Ivermectin + Pyrantel As Pamoate Salt 6
Prednisone 6
Fluralaner 13.64% 12-Week Chew 6
Imidacloprid + Moxidectin 4
Grapiprant 4
Dexamethasone 3

Data Summary

Metric Value
Total reports referencing reaction 194
Reports with fatal outcome 27
Case-fatality rate (reported events) 1390.0%
Species observed 4
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 662.

Hypermetria Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 194 adverse event reports that reference Hypermetria as a reaction term, including 27 reports with a death outcome — a 1390.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 662, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Hypermetria appears most frequently in reports for Dog (171 reports), Cat (17 reports), Horse (5 reports) — with Dog dominating at 171 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (17), Chihuahua (15), Domestic Shorthair (14). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Hypermetria are Milbemycin Oxime + Spinosad (25 reports), Bedinvetmab (21 reports), Afoxolaner (19 reports), Gabapentin (16 reports), with Milbemycin Oxime + Spinosad appearing alongside this reaction in 25 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial