Reaction profile

The FDA adverse-event record for pr-cerebrum, lesion(s)

Name: PR-CEREBRUM, LESION(S) - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

19 FDA reports name pr-cerebrum, lesion(s), a lower-volume reaction in the CVM extract (VeDDRA 99604). Plate stamps and neighbourhood peers follow.

#2194 of 2,481
by report volume (all reactions): 19
reports citing this reaction: 94.7%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. PR-CEREBRUM, LESION(S) has 19 reports now versus 19 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to PR-CEREBRUM, LESION(S) changes

FDA AER · VeDDRA plate

Code 99604 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 19 reports
DEATH-HOT 94.7%
LOWER-Q #2194/2481
PHOTO-FINISH Adaptor, damaged
SPECIES-DOG Dog · 11
DRUG-LEAD Cefovecin Sodium · 5
DESK-WIDE 15 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Adaptor, damaged (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around PR-CEREBRUM, LESION

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around PR-CEREBRUM, LESION(S)

PR-CEREBRUM, LESION(S): high death-coded share in the FDA AER plate

Signature read: PR-CEREBRUM, LESION(S)'s 94.7% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 19 named reports in the openFDA extract. Death-coded share is upper-third: 18 of 19 reports (94.7% of named reports). Nearest volume peer: Adaptor, damaged (±0 reports). Lead species Dog (11). Lead co-reported drug Cefovecin Sodium (5).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 11

Cat 3

Cattle 2

Alpaca 1

Pig 1

Ferret 1

Breeds Most Affected

Domestic (unspecified) 2

Crossbred Canine/dog 2

Crossbred Bovine/Cattle 2

Lhasa Apso 2

Spaniel - King Charles Cavalier 1

Alpaca 1

Retriever - Labrador 1

Shih Tzu 1

Vietnamese Pot Bellied 1

Terrier - West Highland White 1

Associated Drugs

Cefovecin Sodium 5

Imidacloprid + Moxidectin 3

Spinosad 2

Oclacitinib Maleate 2

Gabapentin 2

Diazepam 2

Tulathromycin 1

Albendazole 1

Carprofen 1

Maropitant 1

Doramectin 1

Oxytetracycline Hydrochloride 1

Glucose 1

Prednisone 1

Fentanyl 1

Enrofloxacin 1

Buprenorphine 1

Clindamycin 1

Fish Oil 1

Tramadol 1

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for PR-CEREBRUM, LESION(S) (#2194 of 2,481 by report volume); death-coded 94.7%. PlainBreed reaction plate · death-coded share stamp 94.7% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →