Reaction profile

The FDA adverse-event record for pr-cerebrum, lesion(s)

19 FDA adverse-event reports reference pr-cerebrum, lesion(s) (VeDDRA 99604). See the species, breeds, and drugs most associated with it below.

19
reports citing this reaction
94.7%
death-coded share
Dog
most-affected species
Cefovecin Sodium
most-associated drug
Verify with FDA CVM →
19
Total Reports
18
Deaths
94.7%
Death Rate

Species Most Affected

Dog 11
Cat 3
Cattle 2
Alpaca 1
Pig 1
Ferret 1

Breeds Most Affected

Domestic (unspecified) 2
Crossbred Canine/dog 2
Crossbred Bovine/Cattle 2
Lhasa Apso 2
Spaniel - King Charles Cavalier 1
Alpaca 1
Retriever - Labrador 1
Shih Tzu 1
Vietnamese Pot Bellied 1
Hound - Basset 1

Associated Drugs

Cefovecin Sodium 5
Imidacloprid + Moxidectin 3
Spinosad 2
Oclacitinib Maleate 2
Gabapentin 2
Diazepam 2
Tulathromycin 1
Albendazole 1
Carprofen 1
Maropitant 1
Doramectin 1
Oxytetracycline Hydrochloride 1
Selegiline Hcl 1
Glucose 1
Prednisone 1
Fentanyl 1
Enrofloxacin 1
Buprenorphine 1
Clindamycin 1
Fish Oil 1

PR-CEREBRUM, LESION(S) Reaction Insights

19 reports name PR-CEREBRUM, LESION(S); 18 recorded a death outcome (94.7% of reported events, not a population-level mortality rate). VeDDRA code: 99604.

By species: Dog (11 reports), Cat (3 reports), Cattle (2 reports). By breed: Domestic (unspecified) (2), Crossbred Canine/dog (2), Crossbred Bovine/Cattle (2).

Most co-reported drugs: Cefovecin Sodium (5 reports), Imidacloprid + Moxidectin (3 reports), Spinosad (2 reports), Oclacitinib Maleate (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.