Reaction profile

The FDA adverse-event record for inappropriate packaging or design

153 FDA adverse-event reports reference inappropriate packaging or design (VeDDRA 99974). See the species, breeds, and drugs most associated with it below.

153
reports citing this reaction
0.0%
death-coded share
Unknown
most-affected species
Robenacoxib
most-associated drug
Verify with FDA CVM →
153
Total Reports
0
Deaths
0.0%
Death Rate

Species Most Affected

Unknown 151
Dog 2

Breeds Most Affected

Unknown 151
Chihuahua 1
Dog (unknown) 1

Associated Drugs

Robenacoxib 18
Cyclosporine A 17
Doramectin 12
Ketoprofen;Tulathromycin 8
Levamisole Hydrochloride;Doramectin 8
Nitenpyram 6
Lufenuron + Milbemycin Oxime 5
Betamethasone + Florfenicol + Terbinafine 5
Milbemycin Oxime + Spinosad 4
Meloxicam 4
Cyclosporine 4
Amoxicillin Trihydrate; Clavulanate Potassium ( K-Clavulanate) 3
Spinosad 3
Ivermectin + Pyrantel As Pamoate Salt 3
Oclacitinib Maleate 3
Dinoprost Tromethamine 3
Ivermectin + Pyrantel 3
Oxytetracycline Dihydrate (Oxytetracycline Amphoteric) 3
Firocoxib 2
Oxytetracycline Dihydrate ( Oxytetracycline Amphoteric) 2

Inappropriate packaging or design Reaction Insights

153 reports name Inappropriate packaging or design; 0 recorded a death outcome (0.0% of reported events, not a population-level mortality rate). VeDDRA code: 99974.

By species: Unknown (151 reports), Dog (2 reports). By breed: Unknown (151), Chihuahua (1), Dog (unknown) (1).

Most co-reported drugs: Robenacoxib (18 reports), Cyclosporine A (17 reports), Doramectin (12 reports), Ketoprofen;Tulathromycin (8 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.