Reaction profile

The FDA adverse-event record for difficulty going up/down stairs

256 FDA adverse-event reports reference difficulty going up/down stairs (VeDDRA 2869). See the species, breeds, and drugs most associated with it below.

256
reports citing this reaction
14.1%
death-coded share
Dog
most-affected species
Bedinvetmab
most-associated drug
Verify with FDA CVM →
256
Total Reports
36
Deaths
14.1%
Death Rate

Species Most Affected

Dog 242
Cat 14

Breeds Most Affected

Retriever - Labrador 38
Crossbred Canine/dog 21
Shepherd Dog - German 18
Dog (unknown) 14
Terrier - Bull - American Pit 12
Retriever - Golden 12
Chihuahua 9
Domestic Shorthair 8
Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 7
Sheepdog - Shetland 6

Associated Drugs

Bedinvetmab 127
Pyrantel Pamoate;Sarolaner 28
Gabapentin 28
Carprofen 26
Fluralaner 13.64% 12-Week Chew 21
Maropitant Citrate 14
Grapiprant 13
Ivermectin + Pyrantel As Pamoate Salt 12
Trilostane 9
Anti-Il31 Mab Mcs Lot #1283563 9
Omeprazole 8
Oclacitinib Maleate 8
Rabies Vaccine 7
Afoxolaner 7
Frunevetmab 7
Polysulfated Glycosaminoglycan 7
Adequan 6
Metronidazole 6
Moxidectin 5
Prednisone 5

Difficulty going up/down stairs Reaction Insights

256 reports name Difficulty going up/down stairs; 36 recorded a death outcome (14.1% of reported events, not a population-level mortality rate). VeDDRA code: 2869.

By species: Dog (242 reports), Cat (14 reports). By breed: Retriever - Labrador (38), Crossbred Canine/dog (21), Shepherd Dog - German (18).

Most co-reported drugs: Bedinvetmab (127 reports), Pyrantel Pamoate;Sarolaner (28 reports), Gabapentin (28 reports), Carprofen (26 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.