Reaction profile

The FDA adverse-event record for hyperaemic mucous membrane

253 FDA adverse-event reports reference hyperaemic mucous membrane (VeDDRA 1006). See the species, breeds, and drugs most associated with it below.

253
reports citing this reaction
24.1%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
253
Total Reports
61
Deaths
24.1%
Death Rate

Species Most Affected

Dog 209
Horse 28
Cat 12
Human 2
Pig 1
Donkey 1

Breeds Most Affected

Retriever - Labrador 28
Crossbred Canine/dog 17
Terrier - Bull - American Pit 13
Domestic Shorthair 9
Boxer (German Boxer) 8
Quarter Horse 8
Thoroughbred 8
Shepherd Dog - German 7
Shepherd Dog - Australian 6
Beagle 6

Associated Drugs

Moxidectin 45
Maropitant Citrate 33
Carprofen 23
Milbemycin Oxime + Spinosad 19
Diphenhydramine Hcl 14
Spinosad 11
Dexamethasone 11
Melarsomine Dihydrochloride 10
Ceftiofur Crystalline Free Acid 10
Famotidine 9
Cefovecin 8
Afoxolaner 8
Ivermectin + Pyrantel As Pamoate Salt 8
Isoflurane 8
Ivermectin 7
Propofol 7
Prednisone 7
Oclacitinib Maleate 7
Gabapentin 7
Deracoxib 6

Hyperaemic mucous membrane Reaction Insights

253 reports name Hyperaemic mucous membrane; 61 recorded a death outcome (24.1% of reported events, not a population-level mortality rate). VeDDRA code: 1006.

By species: Dog (209 reports), Horse (28 reports), Cat (12 reports). By breed: Retriever - Labrador (28), Crossbred Canine/dog (17), Terrier - Bull - American Pit (13).

Most co-reported drugs: Moxidectin (45 reports), Maropitant Citrate (33 reports), Carprofen (23 reports), Milbemycin Oxime + Spinosad (19 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.