Reaction profile

The FDA adverse-event record for illness nos

173 FDA adverse-event reports reference illness nos (VeDDRA 99950). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1114 of 2,481
by report volume (all reactions)
173
reports citing this reaction
18.5%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Illness NOS has 173 reports now versus 173 in that prior snapshot: 0 the same number of (0.0%).

Report change
+0
Death-coded reports
+0
Death-coded share
+0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Illness NOS changes

FDA AER · VeDDRA plate

Code 99950 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 173 reports
  • DEATH-ELEV 18.5%
  • MID-PACK #1114/2481
  • PHOTO-FINISH Angioedema
  • SPECIES-DOG Dog · 95
  • DRUG-LEAD Hyaluronate Sodium · 46
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Angioedema (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Illness NOS

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Cough, productive · near174Decreased blood urea… · near174Paraparesis · near174Angioedema · near173Illness NOS · this reaction173Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Illness NOS

What the FDA AER plate says about Illness NOS

Signature read: 32 death-coded reports is the most distinctive absolute-outcome stamp on Illness NOS. Report volume sits in the middle third of the reaction corpus. 32 of 173 reports were death-coded (18.5% of named reports, not a population mortality rate). Nearest volume peer: Angioedema (±0 reports). Lead species Dog (95). Lead co-reported drug Hyaluronate Sodium (46).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Hyaluronate Sodium appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 95
Horse 54
Cattle 10
Cat 9
Pig 2
Chicken 1
Sheep 1
Unknown 1

Breeds Most Affected

Unknown 37
Dog (unknown) 24
Retriever - Labrador 9
Horse (unknown) 8
Retriever - Golden 7
Chihuahua 6
Domestic Shorthair 6
Holstein-Friesian also known as Holstein 4
Crossbred Canine/dog 4
Terrier - Yorkshire 4

Associated Drugs

Hyaluronate Sodium 46
Milbemycin Oxime + Spinosad 22
Spinosad 13
Ivermectin + Pyrantel As Pamoate Salt 10
Monensin Sodium 5
Oclacitinib Maleate 5
Imidacloprid + Moxidectin 4
Lufenuron + Milbemycin Oxime 3
Cefovecin 3
Ivermectin/Pyrantel Pamoate Chewable 272Mcg/652Mg 3
Ivermectin/Pyrantel Pamoate Chewable 68Mcg/163Mg 3
Firocoxib 227 Mg Chewable 3
Carprofen 3
Fluralaner 3
Milbemycin Oxime, Lufenuron 3
Polysulfated Glycosaminoglycan 3
Tulathromycin 2
Bovine Parainfluenza Virus 3, Reisinger(Nl-Bk-6), Mlv; Bovine Respiratory Syncyt 2
Ivermectin(1%)/Clorsulon(10%) Injection 2
Doxycycline 2

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Illness NOS, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (173 here).

Similar death-coded share

Nearest other reactions by death-coded share (18.5% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Illness NOS (#1114 of 2,481 by report volume); death-coded 18.5%. PlainBreed reaction plate · death-coded report count stamp 32 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →