Reaction profile

The FDA adverse-event record for generalised inflammation of eye

27 FDA adverse-event reports reference generalised inflammation of eye (VeDDRA 459). See the species, breeds, and drugs most associated with it below.

27
reports citing this reaction
14.8%
death-coded share
Dog
most-affected species
Enrofloxacin
most-associated drug
Verify with FDA CVM →
27
Total Reports
4
Deaths
14.8%
Death Rate

Species Most Affected

Dog 21
Cat 3
Pig 2
Cattle 1

Breeds Most Affected

Crossbred Canine/dog 3
Siberian Husky 2
Shepherd Dog - Australian 2
Maltese 2
PIC International Commercial Swine Lines 1
Domestic Shorthair 1
Pig (unknown) 1
Cattle (unknown) 1
Shih Tzu 1
Persian 1

Associated Drugs

Enrofloxacin 3
Trilostane 3
Imidacloprid + Moxidectin 3
Narasin 2
Moxidectin 2
Canine Adenovirus Type 2, Manhattan, Mlv; Canine Distemper Virus, N-Cdv, Mlv; Ca 2
Rabies Virus, Kv 2
Phenylpropanolamine 2
Diphenhydramine Hcl 2
Dexamethasone 2
Rabies Vaccine 2
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 2
Bordetella Bronchiseptica + Avirulent Live Culture 2
Pyrantel Pamoate 1
Tacrolimus Ophthalmic Solution 0.02% 1
Vetmedin 1
Pimobendan 1
Furosemide 1
Rabies Vaccination 1
Spironolactone 1

Generalised inflammation of eye Reaction Insights

27 reports name Generalised inflammation of eye; 4 recorded a death outcome (14.8% of reported events, not a population-level mortality rate). VeDDRA code: 459.

By species: Dog (21 reports), Cat (3 reports), Pig (2 reports). By breed: Crossbred Canine/dog (3), Siberian Husky (2), Shepherd Dog - Australian (2).

Most co-reported drugs: Enrofloxacin (3 reports), Trilostane (3 reports), Imidacloprid + Moxidectin (3 reports), Narasin (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.