Reaction profile

The FDA adverse-event record for ptyalism

177 FDA adverse-event reports reference ptyalism (VeDDRA 1075). Plate codes and volume neighbourhood below; species, breeds, and drugs follow.

#1098 of 2,481
by report volume (all reactions)
177
reports citing this reaction
19.2%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Ptyalism has 177 reports now versus 173 in that prior snapshot: 4 more (2.3%).

Report change
+4
Death-coded reports
+2
Death-coded share
+0.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Ptyalism changes

FDA AER · VeDDRA plate

Code 1075 VOL-LOW

VOL-LOW · DEATH-ELEV · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-LOW 177 reports
  • DEATH-ELEV 19.2%
  • MID-PACK #1098/2481
  • PHOTO-FINISH Choke
  • SPECIES-DOG Dog · 136
  • DRUG-LEAD Maropitant Citrate · 29
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Choke (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Report-volume neighbourhood around Ptyalism

Highest and lowest poles plus nearest volume peers, not a full 2,500-reaction corpus board reprint.

Vomiting · highest174348Choke · near177Decreased respiratory… · near177Ptyalism · this reaction177Vascular disorder NOS… · near177Agonal breathing · near176Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Ptyalism

What the FDA AER plate says about Ptyalism

Signature read: 34 death-coded reports is the most distinctive absolute-outcome stamp on Ptyalism. Report volume sits in the middle third of the reaction corpus. 34 of 177 reports were death-coded (19.2% of named reports, not a population mortality rate). Nearest volume peer: Choke (±0 reports). Lead species Dog (136). Lead co-reported drug Maropitant Citrate (29).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Maropitant Citrate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 136
Cat 35
Horse 6

Breeds Most Affected

Domestic Shorthair 19
Retriever - Labrador 18
Dog (unknown) 6
Crossbred Canine/dog 6
Boxer (German Boxer) 5
Retriever - Golden 5
Terrier - Bull - American Pit 4
Terrier - Jack Russell 4
Spitz - German Pomeranian 4
Shepherd Dog - German 4

Associated Drugs

Maropitant Citrate 29
Milbemycin Oxime + Spinosad 21
Carprofen 13
Moxidectin 12
Gabapentin 10
Famotidine 10
Isoflurane 9
Buprenorphine 9
Cefovecin 9
Ondansetron 9
Lotilaner 9
Oclacitinib Maleate 8
Diphenhydramine 8
Meloxicam 7
Spinosad 6
Ivermectin 6
Rabies Vaccine 6
Prednisone 6
Ivermectin + Pyrantel As Pamoate Salt 6
Selamectin 5

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Ptyalism, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (19.2% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Ptyalism (#1098 of 2,481 by report volume); death-coded 19.2%. PlainBreed reaction plate · death-coded report count stamp 34 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →