Reaction profile

The FDA adverse-event record for injection site haematoma

78 FDA adverse-event reports reference injection site haematoma (VeDDRA 80). See the species, breeds, and drugs most associated with it below.

78
reports citing this reaction
16.7%
death-coded share
Dog
most-affected species
Carprofen
most-associated drug
Verify with FDA CVM →
78
Total Reports
13
Deaths
16.7%
Death Rate

Species Most Affected

Dog 51
Horse 9
Cat 6
Human 6
Cattle 5
Chicken 1

Breeds Most Affected

Unknown 7
Retriever - Labrador 5
Retriever - Golden 4
Domestic Shorthair 3
Domestic Longhair 3
Crossbred Canine/dog 3
Dog (unknown) 3
Mixed (Cattle) 2
Terrier - Yorkshire 2
Beagle 2

Associated Drugs

Carprofen 12
Moxidectin 11
Polysulfated Glycosaminoglycan 8
Gabapentin 8
Maropitant Citrate 7
Ceftiofur Crystalline Free Acid 6
Prednisone 6
Melarsomine Dihydrochloride 5
Meloxicam 4
Diphenhydramine Hcl 3
Cefovecin 3
Bupivacaine 3
Anesthetic (Unknown) 3
Bedinvetmab 3
Dexamethasone 2
Vitamin K1 2
Tilmicosin 2
Butorphanol Tartrate 2
Isoflurane 2
Amoxicillin 2

Injection site haematoma Reaction Insights

78 reports name Injection site haematoma; 13 recorded a death outcome (16.7% of reported events, not a population-level mortality rate). VeDDRA code: 80.

By species: Dog (51 reports), Horse (9 reports), Cat (6 reports). By breed: Unknown (7), Retriever - Labrador (5), Retriever - Golden (4).

Most co-reported drugs: Carprofen (12 reports), Moxidectin (11 reports), Polysulfated Glycosaminoglycan (8 reports), Gabapentin (8 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.