Reaction profile

The FDA adverse-event record for immune mediated thrombocytopenia

705 FDA adverse-event reports reference immune mediated thrombocytopenia (VeDDRA 2009). See the species, breeds, and drugs most associated with it below.

705
reports citing this reaction
26.1%
death-coded share
Dog
most-affected species
Moxidectin
most-associated drug
Verify with FDA CVM →
705
Total Reports
184
Deaths
26.1%
Death Rate

Species Most Affected

Dog 686
Cat 16
Horse 3

Breeds Most Affected

Retriever - Labrador 65
Retriever - Golden 47
Crossbred Canine/dog 42
Shih Tzu 26
Chihuahua 25
Dog (unknown) 21
Maltese 20
Terrier (unspecified) 16
Shepherd Dog - German 15
Spitz - German Pomeranian 15

Associated Drugs

Moxidectin 112
Bedinvetmab 76
Milbemycin Oxime + Spinosad 73
Carprofen 70
Maropitant Citrate 65
Prednisone 64
Oclacitinib Maleate 44
Doxycycline 42
Fluralaner Chew Tablets 38
Anti-Il31 Mab Mcs Lot #1283563 38
Cyclosporine 37
Gabapentin 36
Pyrantel Pamoate;Sarolaner 32
Cefovecin 29
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 29
Afoxolaner 28
Grapiprant 25
Fluralaner 13.64% 12-Week Chew 23
Metronidazole 22
Bordetella Vaccine 19

Immune mediated thrombocytopenia Reaction Insights

705 reports name Immune mediated thrombocytopenia; 184 recorded a death outcome (26.1% of reported events, not a population-level mortality rate). VeDDRA code: 2009.

By species: Dog (686 reports), Cat (16 reports), Horse (3 reports). By breed: Retriever - Labrador (65), Retriever - Golden (47), Crossbred Canine/dog (42).

Most co-reported drugs: Moxidectin (112 reports), Bedinvetmab (76 reports), Milbemycin Oxime + Spinosad (73 reports), Carprofen (70 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.