Immune mediated thrombocytopenia

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VeDDRA Code: 2009

705 adverse event reports referencing this reaction

705
Total Reports
184
Deaths
2610.0%
Death Rate

Species Most Affected

Dog 686
Cat 16
Horse 3

Breeds Most Affected

Retriever - Labrador 65
Retriever - Golden 47
Crossbred Canine/dog 42
Shih Tzu 26
Chihuahua 25
Dog (unknown) 21
Maltese 20
Terrier (unspecified) 16
Shepherd Dog - German 15
Spitz - German Pomeranian 15

Associated Drugs

Moxidectin 112
Bedinvetmab 76
Milbemycin Oxime + Spinosad 73
Carprofen 70
Maropitant Citrate 65
Prednisone 64
Oclacitinib Maleate 44
Doxycycline 42
Fluralaner Chew Tablets 38
Anti-Il31 Mab Mcs Lot #1283563 38
Cyclosporine 37
Gabapentin 36
Pyrantel Pamoate;Sarolaner 32
Cefovecin 29
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 29
Afoxolaner 28
Grapiprant 25
Fluralaner 13.64% 12-Week Chew 23
Metronidazole 22
Bordetella Vaccine 19

Data Summary

Metric Value
Total reports referencing reaction 705
Reports with fatal outcome 184
Case-fatality rate (reported events) 2610.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 2009.

Immune mediated thrombocytopenia Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 705 adverse event reports that reference Immune mediated thrombocytopenia as a reaction term, including 184 reports with a death outcome — a 2610.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 2009, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Immune mediated thrombocytopenia appears most frequently in reports for Dog (686 reports), Cat (16 reports), Horse (3 reports) — with Dog dominating at 686 entries. Within those species, the breeds most often named alongside this reaction are Retriever - Labrador (65), Retriever - Golden (47), Crossbred Canine/dog (42). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Immune mediated thrombocytopenia are Moxidectin (112 reports), Bedinvetmab (76 reports), Milbemycin Oxime + Spinosad (73 reports), Carprofen (70 reports), with Moxidectin appearing alongside this reaction in 112 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial