Reaction profile

The FDA adverse-event record for immune mediated thrombocytopenia

749 FDA reports name immune mediated thrombocytopenia, a high-volume reaction in the CVM extract (VeDDRA 2009). Plate stamps and neighbourhood peers follow.

#485 of 2,481
by report volume (all reactions)
749
reports citing this reaction
25.6%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Immune mediated thrombocytopenia has 749 reports now versus 731 in that prior snapshot: 18 more (2.5%).

Report change
+18
Death-coded reports
+3
Death-coded share
−0.2 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Immune mediated thrombocytopenia changes

FDA AER · VeDDRA plate

Code 2009 VOL-MID

VOL-MID · DEATH-HOT · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 749 reports
  • DEATH-HOT 25.6%
  • UPPER-Q #485/2481
  • PHOTO-FINISH Shock
  • SPECIES-DOG Dog · 730
  • DRUG-LEAD Moxidectin · 122
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Shock (±8 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Immune mediated thrombocytopenia

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Decreased body temper… · near760General pain (see oth… · near758Shock · near757Immune mediated throm… · thi…749Dullness · near739Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Immune mediated thrombocytopenia

Immune mediated thrombocytopenia: high death-coded share in the FDA AER plate

Signature read: 192 death-coded reports is a heavy tail count for Immune mediated thrombocytopenia in the CVM extract. Report volume is upper-third scale: 749 named reports in the openFDA extract. Death-coded share is upper-third: 192 of 749 reports (25.6% of named reports). Nearest volume peer: Shock (±8 reports). Lead species Dog (730). Lead co-reported drug Moxidectin (122).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 730
Cat 16
Horse 3

Breeds Most Affected

Retriever - Labrador 68
Crossbred Canine/dog 50
Retriever - Golden 48
Chihuahua 28
Shih Tzu 26
Dog (unknown) 23
Maltese 21
Terrier - Bull - American Pit 20
Terrier (unspecified) 19
Shepherd Dog - German 16

Associated Drugs

Moxidectin 122
Maropitant Citrate 82
Bedinvetmab 81
Carprofen 77
Milbemycin Oxime + Spinosad 73
Prednisone 70
Oclacitinib Maleate 45
Anti-Il31 Mab Mcs Lot #1283563 45
Doxycycline 44
Gabapentin 41
Cyclosporine 40
Fluralaner Chew Tablets 38
Pyrantel Pamoate;Sarolaner 37
Leptospira Canicola L-15 Strain C-51;Leptospira Grippotyphosa 1550 Lot 10005 Str 35
Cefovecin 30
Afoxolaner 28
Fluralaner 13.64% 12-Week Chew 27
Metronidazole 25
Grapiprant 25
Enrofloxacin 20

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Immune mediated thrombocytopenia, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar report volume

Nearest other reactions by FDA report count (749 here).

Similar death-coded share

Nearest other reactions by death-coded share (25.6% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Immune mediated thrombocytopenia (#485 of 2,481 by report volume); death-coded 25.6%. PlainBreed reaction plate · death-coded report count stamp 192 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →