Reaction profile

The FDA adverse-event record for hypertrichosis

31 FDA adverse-event reports reference hypertrichosis (VeDDRA 2180). See the species, breeds, and drugs most associated with it below.

31
reports citing this reaction
3.2%
death-coded share
Horse
most-affected species
Pergolide Mesylate
most-associated drug
Verify with FDA CVM →
31
Total Reports
1
Deaths
3.2%
Death Rate

Species Most Affected

Horse 15
Dog 14
Cat 1
Donkey 1

Breeds Most Affected

Horse (unknown) 7
Retriever - Golden 2
Dog (unknown) 2
Morgan 2
Quarter Horse 2
Retriever - Labrador 2
Shih Tzu 2
Pit Bull 1
Bulldog - French 1
Warmblood (unspecified) 1

Associated Drugs

Pergolide Mesylate 11
Cyclosporine 6
Milbemycin Oxime + Spinosad 5
Prednisone 3
Trilostane 3
Dexamethasone Sodium Phosphate 3
Spinosad 2
Polysulfated Glycosaminoglycan 2
Carprofen 2
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 2
Eye Wash Solution 2
Maropitant Citrate 2
Fluids 2
Eye Lubricant 2
Pilocarpine 2% 2
Cyclosporine A 1
Ivermectin + Pyrantel As Pamoate Salt 1
Afoxolaner 1
Fluralaner Chew Tablets 1
Chloroxylenol + Salicylic Acid 1

Hypertrichosis Reaction Insights

31 reports name Hypertrichosis; 1 recorded a death outcome (3.2% of reported events, not a population-level mortality rate). VeDDRA code: 2180.

By species: Horse (15 reports), Dog (14 reports), Cat (1 reports). By breed: Horse (unknown) (7), Retriever - Golden (2), Dog (unknown) (2).

Most co-reported drugs: Pergolide Mesylate (11 reports), Cyclosporine (6 reports), Milbemycin Oxime + Spinosad (5 reports), Prednisone (3 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.