Reaction profile

The FDA adverse-event record for hypertrichosis

32 FDA reports name hypertrichosis, a lower-volume reaction in the CVM extract (VeDDRA 2180). Plate stamps and neighbourhood peers follow.

#1958 of 2,481
by report volume (all reactions)
32
reports citing this reaction
3.1%
death-coded share
Horse
most-affected species
Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Hypertrichosis has 32 reports now versus 31 in that prior snapshot: 1 more (3.2%).

Report change
+1
Death-coded reports
+0
Death-coded share
−0.1 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Hypertrichosis changes

FDA AER · VeDDRA plate

Code 2180 VOL-TRACE

VOL-TRACE · DEATH-LOW · LOWER-Q · PHOTO-FINISH · SPECIES-HORSE · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-TRACE 32 reports
  • DEATH-LOW 3.1%
  • LOWER-Q #1958/2481
  • PHOTO-FINISH ANION GAP HI, BLD
  • SPECIES-HORSE Horse · 15
  • DRUG-LEAD Pergolide Mesylate · 11
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: ANION GAP HI, BLD (±0 reports)

Instrument codes from this reaction’s FDA CVM adverse-event extract: volume band, death-coded share, corpus rank, photo-finish peer, lead species, lead drug, breed desk, and book completeness. Not a clinical diagnosis.

Lower-volume neighbourhood around Hypertrichosis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348ANION GAP HI, BLD · near32Application site haem… · near32Convulsive disorder N… · near32Copper toxicity signs · near32Hypertrichosis · this reacti…32Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Hypertrichosis

Hypertrichosis: low death-coded share in the FDA AER plate

Signature read: 1 death-coded reports is a thin tail count for Hypertrichosis in the CVM extract. Report volume is lower-third scale: 32 named reports in the openFDA extract. Death-coded share is lower-third: 1 of 32 reports (3.1% of named reports). Nearest volume peer: ANION GAP HI, BLD (±0 reports). Lead species Horse (15). Lead co-reported drug Pergolide Mesylate (11).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Pergolide Mesylate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Horse 15
Dog 14
Cat 2
Donkey 1

Breeds Most Affected

Horse (unknown) 7
Retriever - Golden 2
Dog (unknown) 2
Morgan 2
Quarter Horse 2
Retriever - Labrador 2
Shih Tzu 2
Pit Bull 1
Bulldog - French 1
Warmblood (unspecified) 1

Associated Drugs

Pergolide Mesylate 11
Cyclosporine 6
Milbemycin Oxime + Spinosad 5
Prednisone 3
Trilostane 3
Dexamethasone Sodium Phosphate 3
Spinosad 2
Polysulfated Glycosaminoglycan 2
Carprofen 2
Florfenicol + Mometasone Furoate + Terbinafine Hydrochloride 2
Eye Wash Solution 2
Maropitant Citrate 2
Fluids 2
Eye Lubricant 2
Pilocarpine 2% 2
Cyclosporine A 1
Ivermectin + Pyrantel As Pamoate Salt 1
Afoxolaner 1
Fluralaner Chew Tablets 1
Chloroxylenol + Salicylic Acid 1

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Hypertrichosis (#1958 of 2,481 by report volume); death-coded 3.1%. PlainBreed reaction plate · death-coded report count stamp 1 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →