Reaction profile

The FDA adverse-event record for tongue paralysis

22 FDA adverse-event reports reference tongue paralysis (VeDDRA 2108). See the species, breeds, and drugs most associated with it below.

22
reports citing this reaction
31.8%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
22
Total Reports
7
Deaths
31.8%
Death Rate

Species Most Affected

Dog 15
Horse 5
Cat 2

Breeds Most Affected

Bulldog - French 2
Shepherd Dog - Australian 2
Thoroughbred 2
Boxer (German Boxer) 1
Terrier (unspecified) 1
Cat (unknown) 1
Doberman Pinscher 1
Pointing Dog - German Short-haired 1
Paint 1
Domestic Shorthair 1

Associated Drugs

Milbemycin Oxime + Spinosad 3
Prednisone 3
Ceftiofur Crystalline Free Acid 3
Afoxolaner 2
Cyclosporine A 1
Unknown Monthly Heartworm Preventative 1
Imidacloprid + Moxidectin 1
Praziquantel 1
Methocarbamol 1
Subcutaneous Fluids 1
Intravenous Fluids 1
Chloramphenicol 1
Pyrantel Pamoate 1
Flunixin Meglumine 1
Phenylbutazone 1
Ivermectin(1.55%)/Praziquantel(7.75%) Paste 1
Rabacfosadine Succinate 1
Milbemycin Oxime, Lufenuron 1
Clenbuterol Hydrochloride 1
Eastern Encephalomyelitis Virus, Killed Virus + Equine Influenza Virus, Killed Virus + Equine Rhinopneumonitis Virus, Killed Virus + Tetanus Toxoid + West Nile Virus, Killed Virus + Western Encephalomyelitis Virus, Killed Virus 1

Tongue paralysis Reaction Insights

22 reports name Tongue paralysis; 7 recorded a death outcome (31.8% of reported events, not a population-level mortality rate). VeDDRA code: 2108.

By species: Dog (15 reports), Horse (5 reports), Cat (2 reports). By breed: Bulldog - French (2), Shepherd Dog - Australian (2), Thoroughbred (2).

Most co-reported drugs: Milbemycin Oxime + Spinosad (3 reports), Prednisone (3 reports), Ceftiofur Crystalline Free Acid (3 reports), Afoxolaner (2 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.