Reaction profile

The FDA adverse-event record for cutaneous necrosis

Name: Cutaneous necrosis - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

39 FDA reports name cutaneous necrosis, a lower-volume reaction in the CVM extract (VeDDRA 1203). Plate stamps and neighbourhood peers follow.

#1859 of 2,481
by report volume (all reactions): 39
reports citing this reaction: 35.9%
death-coded share: Dog
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Cutaneous necrosis has 39 reports now versus 39 in that prior snapshot: 0 the same number of (0.0%).

Report change: +0
Death-coded reports: +0
Death-coded share: +0.0 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Cutaneous necrosis changes

FDA AER · VeDDRA plate

Code 1203 VOL-TRACE

VOL-TRACE · DEATH-HOT · MID-PACK · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 39 reports
DEATH-HOT 35.9%
MID-PACK #1859/2481
PHOTO-FINISH Adaptor, missing
SPECIES-DOG Dog · 32
DRUG-LEAD Carprofen · 9
DESK-WIDE 20 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Adaptor, missing (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Cutaneous necrosis

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Cutaneous necrosis

Cutaneous necrosis: high death-coded share in the FDA AER plate

Signature read: Cutaneous necrosis's 35.9% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 39 named reports in the openFDA extract. Death-coded share is upper-third: 14 of 39 reports (35.9% of named reports). Nearest volume peer: Adaptor, missing (±0 reports). Lead species Dog (32). Lead co-reported drug Carprofen (9).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 32

Cat 4

Chicken 2

Horse 1

Breeds Most Affected

Shih Tzu 4

Domestic Shorthair 3

Retriever - Golden 3

Retriever - Labrador 2

Chicken (unknown) 2

Dachshund - Miniature 2

Havanese 2

Spaniel - King Charles Cavalier 2

Bulldog - American 1

Greyhound 1

Associated Drugs

Carprofen 9

Maropitant Citrate 6

Cefovecin 4

Gabapentin 4

Propofol 4

Isoflurane 4

Trilostane 3

Robenacoxib 3

Meloxicam 3

Antibiotic 3

Amoxicillin Trihydrate;Clavulanate Potassium ( K-Clavulanate) 3

Buprenorphine 3

Moxidectin 3

Trazadone 3

Bordetella Bronchiseptica, Strain 78-9159, Kb 2

Diphenhydramine Hcl 2

Tramadol 2

Milbemycin Oxime + Spinosad 2

Deracoxib 2

Dexmedetomidine Hydrochloride 2

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Cutaneous necrosis (#1859 of 2,481 by report volume); death-coded 35.9%. PlainBreed reaction plate · death-coded share stamp 35.9% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →