Reaction profile

The FDA adverse-event record for kidney atrophy

Name: Kidney atrophy - FDA Animal Adverse Reaction
Creator: PlainBreed
License: https://open.fda.gov/license/

21 FDA reports name kidney atrophy, a lower-volume reaction in the CVM extract (VeDDRA 2984). Plate stamps and neighbourhood peers follow.

#2143 of 2,481
by report volume (all reactions): 21
reports citing this reaction: 52.4%
death-coded share: Cat
most-affected species

Compiled by PlainBreed

Verify with FDA CVM →

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Kidney atrophy has 21 reports now versus 20 in that prior snapshot: 1 more (5.0%).

Report change: +1
Death-coded reports: +0
Death-coded share: −2.6 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Kidney atrophy changes

FDA AER · VeDDRA plate

Code 2984 VOL-TRACE

VOL-TRACE · DEATH-HOT · LOWER-Q · PHOTO-FINISH · SPECIES-CAT · DRUG-LEAD · DESK-WIDE · BOOK-FULL

VOL-TRACE 21 reports
DEATH-HOT 52.4%
LOWER-Q #2143/2481
PHOTO-FINISH Chewing - pruritus
SPECIES-CAT Cat · 13
DRUG-LEAD Maropitant Citrate · 7
DESK-WIDE 10 breeds
BOOK-FULL 8/8 fields

Nearest volume peer: Chewing - pruritus (±0 reports)

Upper-third death-coded share drives the outcome stamps on this plate; volume band, corpus rank, and co-report peers follow. Not a clinical diagnosis.

Lower-volume neighbourhood around Kidney atrophy

Lower-third volume poles plus nearest peers, not a full reaction corpus board reprint.

FDA AER report volume · neighbourhood around Kidney atrophy

Kidney atrophy: high death-coded share in the FDA AER plate

Signature read: Kidney atrophy's 52.4% death-coded share is among the highest in the openFDA reaction corpus. Report volume is lower-third scale: 21 named reports in the openFDA extract. Death-coded share is upper-third: 11 of 21 reports (52.4% of named reports). Nearest volume peer: Chewing - pruritus (±0 reports). Lead species Cat (13). Lead co-reported drug Maropitant Citrate (7).

Read these counts as reporting volume, not risk: per our methodology, A high death-coded share in FDA filings does not prove causation; co-reporting is voluntary temporal association only. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Cat 13

Dog 8

Breeds Most Affected

Domestic Shorthair 10

Domestic Longhair 2

Bulldog - French 2

Cat (other) 1

Retriever - Labrador 1

Cattle Dog - Australian (blue heeler, red heeler, Queensland cattledog) 1

Chihuahua 1

Spitz - German Pomeranian 1

Retriever - Golden 1

Dog (unknown) 1

Associated Drugs

Maropitant Citrate 7

Bedinvetmab 7

Frunevetmab 6

Isoflurane 5

Furosemide 5

Buprenorphine 4

Doxycycline 3

Gabapentin 3

Molidustat 2

Carprofen 2

Psyllium 2

Meclizine 2

Bupivicaine 2

Atipamezole 2

Phosphate Binder 2

Renal Support Supplement 2

Famotidine 2

Sucralfate 2

Amlodipine 2

Glucosamine Chondroitin 2

What to do with this reaction

Read how death-coded share differs from a mortality rate before drawing conclusions. Understanding adverse events
Browse the full reaction directory to compare report counts across reaction types. All reactions

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Kidney atrophy (#2143 of 2,481 by report volume); death-coded 52.4%. PlainBreed reaction plate · death-coded share stamp 52.4% · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →