Excessive chewing, licking and/or grooming

Verify with FDA CVM →

VeDDRA Code: 1974

626 adverse event reports referencing this reaction

626
Total Reports
9
Deaths
140.0%
Death Rate

Species Most Affected

Cat 465
Dog 160
Other Rodents 1

Breeds Most Affected

Domestic Shorthair 246
Domestic Longhair 49
Domestic Mediumhair 41
Cat (unknown) 37
Crossbred Canine/dog 19
Maine Coon 15
Siamese 14
Cat (other) 11
Retriever - Labrador 11
Shepherd Dog - German 10

Associated Drugs

Nitenpyram 174
Frunevetmab 95
Selamectin;Sarolaner 40
Fluralaner Spot-On Solution 36
Lotilaner 31
Gabapentin 26
Bedinvetmab 26
Pyrantel Pamoate;Sarolaner 24
Fluralaner/Moxidectin Spot-On 22
Selamectin 19
Fluralaner 13.64% 12-Week Chew 14
Imidacloprid + Moxidectin 13
Oclacitinib Maleate 11
Trilostane 10
Buprenorphine 10
Eprinomectin + Esafoxolaner + Praziquantel 10
Methylprednisolone Acetate 9
Carprofen 9
Cyclosporine 9
Prednisolone 9

Data Summary

Metric Value
Total reports referencing reaction 626
Reports with fatal outcome 9
Case-fatality rate (reported events) 140.0%
Species observed 3
Breeds observed 20
Drugs associated with reaction 20

Source: FDA Center for Veterinary Medicine — Adverse Event Reporting (CVM AER); reaction term coded under VeDDRA 1974.

Excessive chewing, licking and/or grooming Reaction Insights

The FDA Center for Veterinary Medicine database currently lists 626 adverse event reports that reference Excessive chewing, licking and/or grooming as a reaction term, including 9 reports with a death outcome — a 140.0% case-fatality figure calculated across only those events where this reaction was coded. The reaction is indexed in the openFDA system under VeDDRA code 1974, the standardized veterinary dictionary used to normalize clinical signs across submitters. Because reports are voluntary and often describe multiple concurrent signs per animal, the volume here reflects reporting intensity rather than true incidence in the broader pet population.

Excessive chewing, licking and/or grooming appears most frequently in reports for Cat (465 reports), Dog (160 reports), Other Rodents (1 reports) — with Cat dominating at 465 entries. Within those species, the breeds most often named alongside this reaction are Domestic Shorthair (246), Domestic Longhair (49), Domestic Mediumhair (41). These distributions are influenced both by underlying breed popularity and by how veterinarians and owners code a given clinical sign, so they should be interpreted as a reporting fingerprint rather than a pure susceptibility ranking.

The drugs most commonly co-reported with Excessive chewing, licking and/or grooming are Nitenpyram (174 reports), Frunevetmab (95 reports), Selamectin;Sarolaner (40 reports), Fluralaner Spot-On Solution (36 reports), with Nitenpyram appearing alongside this reaction in 174 submissions. Co-reporting does not establish that any specific product caused the reaction — FDA CVM data captures temporal association only. The value of these aggregates is in flagging which therapeutic classes appear repeatedly alongside a given clinical sign, so owners and veterinarians can ask targeted questions about medications currently in use.

Source: FDA Center for Veterinary Medicine — Adverse Event Reports FDA Center for Veterinary Medicine — Adverse Event Reports Data reflects voluntary submissions and may not represent actual incidence rates

Related

Data sourced from official AKC, AVMA, ACVO, and breed-club veterinary references. See our methodology for details. Retrieved and formatted by PlainBreed Editorial