Reaction profile

The FDA adverse-event record for regurgitation

1,136 FDA reports name regurgitation, a high-volume reaction in the CVM extract (VeDDRA 1888). Plate stamps and neighbourhood peers follow.

#353 of 2,481
by report volume (all reactions)
1,136
reports citing this reaction
17.1%
death-coded share
Dog
most-affected species

Release-over-release change

What changed in the latest FDA data snapshot

PlainBreed reconstructed the prior snapshot from dated openFDA partitions through 2025 Q4, then compared it with the 2026-07-27 openFDA export. Regurgitation has 1,136 reports now versus 1,109 in that prior snapshot: 27 more (2.4%).

Report change
+27
Death-coded reports
+12
Death-coded share
+0.7 pts

This compares reported-event counts in two source snapshots. It does not establish a change in real-world risk, product safety, or disease incidence.

Subscribe to Regurgitation changes

FDA AER · VeDDRA plate

Code 1888 VOL-MID

VOL-MID · DEATH-ELEV · UPPER-Q · PHOTO-FINISH · SPECIES-DOG · DRUG-LEAD · DESK-WIDE · BOOK-FULL

  • VOL-MID 1,136 reports
  • DEATH-ELEV 17.1%
  • UPPER-Q #353/2481
  • PHOTO-FINISH Tubes, Damaged
  • SPECIES-DOG Dog · 1,040
  • DRUG-LEAD Maropitant Citrate · 201
  • DESK-WIDE 20 breeds
  • BOOK-FULL 8/8 fields

Nearest volume peer: Tubes, Damaged (±0 reports)

Upper-third report volume drives the scale stamps on this plate; death-coded share and co-report peers follow. Not a clinical diagnosis.

High-volume neighbourhood around Regurgitation

Upper-third volume poles plus nearest peers, not a full reaction corpus board reprint.

Vomiting · highest174348Hypothyroidism · near1137Regurgitation · this reaction1136Tubes, Damaged · near1136Low sodium-potassium… · near1134Anaphylactic-type rea… · near1132Urinary tract neoplas… · low…10
FDA AER report volume · neighbourhood around Regurgitation

What the FDA AER plate says about Regurgitation

Signature read: 194 death-coded reports is a heavy tail count for Regurgitation in the CVM extract. Report volume is upper-third scale: 1,136 named reports in the openFDA extract. 194 of 1,136 reports were death-coded (17.1% of named reports, not a population mortality rate). Nearest volume peer: Tubes, Damaged (±0 reports). Lead species Dog (1,040). Lead co-reported drug Maropitant Citrate (201).

Read these counts as reporting volume, not risk: per our methodology, Lead co-reported drug Maropitant Citrate appears in filings alongside this reaction; that is association, not causation. Browse the full reactions index or the about page for how PlainBreed frames FDA CVM extracts.

Species Most Affected

Dog 1,040
Cat 77
Horse 6
Human 3
Parrot 2
Turtle 2
Other 2
Snake 1
Pig 1
Pigeon 1

Breeds Most Affected

Retriever - Labrador 124
Crossbred Canine/dog 68
Dog (unknown) 57
Retriever - Golden 46
Domestic Shorthair 36
Terrier - Yorkshire 35
Pit Bull 32
Boxer (German Boxer) 30
Bulldog - French 29
Terrier - Bull - American Pit 28

Associated Drugs

Maropitant Citrate 201
Carprofen 120
Milbemycin Oxime + Spinosad 98
Gabapentin 91
Deracoxib 60
Enrofloxacin 58
Afoxolaner 56
Propofol 55
Metoclopramide 54
Butorphanol 50
Bedinvetmab 49
Tramadol 48
Isoflurane 48
Ivermectin + Pyrantel As Pamoate Salt 48
Buprenorphine 47
Midazolam 45
Moxidectin 43
Famotidine 41
Oclacitinib Maleate 41
Meloxicam 40

Nationwide reactions with similar profiles

Two openFDA-derived peer sets for Regurgitation, both floored at ≥50 reports so the neighborhoods stay in the advertised mass (the volume chart above is the unfloored photo-finish strip).

Similar death-coded share

Nearest other reactions by death-coded share (17.1% here), distinct from the volume row.

What to do with this reaction

A report does not prove a drug caused the reaction; consult a veterinarian before acting on this data.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

openFDA Animal & Veterinary Adverse Events (FDA CVM) for Regurgitation (#353 of 2,481 by report volume); death-coded 17.1%. PlainBreed reaction plate · death-coded report count stamp 194 · vintage 2025.

Informational only. FDA adverse-event reports are voluntary and do not prove causation; consult a veterinarian before acting on them. Verify with FDA CVM →