Reaction profile

The FDA adverse-event record for tense abdomen

1,189 FDA adverse-event reports reference tense abdomen (VeDDRA 1978). See the species, breeds, and drugs most associated with it below.

1,189
reports citing this reaction
22.0%
death-coded share
Dog
most-affected species
Milbemycin Oxime + Spinosad
most-associated drug
Verify with FDA CVM →
1,189
Total Reports
262
Deaths
22.0%
Death Rate

Species Most Affected

Dog 1,105
Cat 77
Horse 4
Other Canids 1
Cattle 1
Goat 1

Breeds Most Affected

Retriever - Labrador 120
Crossbred Canine/dog 74
Terrier - Yorkshire 62
Chihuahua 49
Domestic Shorthair 47
Maltese 45
Retriever - Golden 41
Shepherd Dog - German 40
Shih Tzu 37
Beagle 37

Associated Drugs

Milbemycin Oxime + Spinosad 196
Carprofen 132
Maropitant Citrate 125
Afoxolaner 69
Gabapentin 59
Spinosad 58
Deracoxib 58
Oclacitinib Maleate 55
Fluralaner Chew Tablets 55
Moxidectin 51
Tramadol 45
Pyrantel Pamoate;Sarolaner 45
Grapiprant 44
Ivermectin + Pyrantel As Pamoate Salt 43
Fluralaner 13.64% 12-Week Chew 41
Metronidazole 35
Buprenorphine 35
Rabies Vaccine 32
Enrofloxacin 31
Butorphanol 30

Tense abdomen Reaction Insights

1,189 reports name Tense abdomen; 262 recorded a death outcome (22.0% of reported events, not a population-level mortality rate). VeDDRA code: 1978.

By species: Dog (1,105 reports), Cat (77 reports), Horse (4 reports). By breed: Retriever - Labrador (120), Crossbred Canine/dog (74), Terrier - Yorkshire (62).

Most co-reported drugs: Milbemycin Oxime + Spinosad (196 reports), Carprofen (132 reports), Maropitant Citrate (125 reports), Afoxolaner (69 reports).

Read these counts as reporting volume, not risk: per our methodology, co-reporting reflects temporal association captured in voluntary submissions, not proof that a drug caused this reaction. A widely-prescribed drug will rack up more raw co-reports at an identical true rate than a rarely-used one, so compare within similar-exposure products.

Source: FDA Center for Veterinary Medicine openFDA Animal & Veterinary Adverse Events (CVM AER) · 2025

Every figure on PlainBreed is rendered directly from FDA openFDA adverse event data, no number is typed in by an editor. This page draws directly on FDA openFDA data, no figure is typed in by an editor. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.